Evidence map›Paper›PMID 41136803›Full record

ArticleSpine deformity2026

Paediatric neuromuscular scoliosis and post-operative blood pressure targets: a retrospective analysis.

Grace Pulling, Lionel D Rayward, Anthony Slater, Maree T Izatt, Adam F Parr, Simon C Gatehouse, Robert D Labrom, Geoffrey N Askin, J Paige Little

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In one paragraph

Article in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Grace PullingBiomechanics and Spine Research Group, School of Mechanical, Medical and Process Engineering, Queensland University of Technology (QUT), South Brisbane, Australia. g.pulling@hdr.qut.edu.au.ORCID http://orcid.org/0009-0008-3750-7493
Lionel D RaywardBiomechanics and Spine Research Group, School of Mechanical, Medical and Process Engineering, Queensland University of Technology (QUT), South Brisbane, Australia.
Anthony SlaterDepartment of Paediatric Intensive Care Medicine, Children's Health Queensland Hospital and Health Service, South Brisbane, Australia.
Maree T IzattBiomechanics and Spine Research Group, School of Mechanical, Medical and Process Engineering, Queensland University of Technology (QUT), South Brisbane, Australia.
Adam F ParrBiomechanics and Spine Research Group, School of Mechanical, Medical and Process Engineering, Queensland University of Technology (QUT), South Brisbane, Australia.
Simon C GatehouseBiomechanics and Spine Research Group, School of Mechanical, Medical and Process Engineering, Queensland University of Technology (QUT), South Brisbane, Australia.
Robert D LabromBiomechanics and Spine Research Group, School of Mechanical, Medical and Process Engineering, Queensland University of Technology (QUT), South Brisbane, Australia.
Geoffrey N AskinBiomechanics and Spine Research Group, School of Mechanical, Medical and Process Engineering, Queensland University of Technology (QUT), South Brisbane, Australia.
J Paige LittleBiomechanics and Spine Research Group, School of Mechanical, Medical and Process Engineering, Queensland University of Technology (QUT), South Brisbane, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study investigates blood pressure variations and clinical outcomes in paediatric neuromuscular scoliosis patients after deformity correction surgery to mitigate the risk of ischaemic spinal cord injury (SCI). Hypotension is proposed as an aetiological mechanism for delayed SCI, but there is limited evidence regarding the frequency, severity, duration, and clinical effect of hypotension exposure in the immediate post-operative period.

methodsThis is a retrospective review of 94 patients with cerebral palsy or CP-like conditions, who underwent posterior spinal instrumentation at Queensland Children's Hospital. Post-operative mean arterial pressure (MAP) variations and associations with tissue perfusion markers were analysed. Hypotension was described using area under threshold (AUT) and time under threshold (TUT) for MAP thresholds of 40-80 mmHg.

results14.9% of patients experienced an episode of hypotension under 60 mmHg lasting ≥ 60 min, compared to 62.4% at 70 mmHg. At the 60 mmHg threshold, mean TUT was 9.2%, 95% CI [6.55, 11.8], compared to 40.9%, 95% CI [35.1, 46.6] at 70 mmHg. Logistic regression revealed increased hypotension exposure under thresholds of 60 and 65 mmHg over a 60-min period was associated with increased risk of hyperlactataemia (AUT, 60 mmHg threshold β = 2.85, OR 17, p = 0.03, 95% CI [0.22-5.48]. Increased AUT exposure was associated with low urine output at thresholds ≥ 60 mmHg over 30 min. Haemoglobin ≤ 80 g/L was associated with elevated lactate.

conclusionPeriods of sustained hypotension were common and usually without neurologic sequalae; however, a MAP below 60 and 65 mmHg sustained for 60 min was associated with surrogate markers of global tissue hypoperfusion.

Indexed as

Blood PressureHypotensionNeuromuscular DiseasesPostoperative ComplicationsScoliosisSpinal FusionAdolescentCerebral PalsyChildChild, PreschoolFemaleHumansMalePostoperative PeriodRetrospective StudiesSpinal Cord IschemiaBlood pressureDelayed spinal cord injuryMean arterial pressureNeuromuscular scoliosisPaediatricsSpine deformity

Identifiers

PMID41136803
PMCPMC12909380

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.