Evidence map›Paper›PMID 41136773›Full record

ArticleNature biotechnology2025

Democratizing protein language model training, sharing and collaboration.

Jin Su, Zhikai Li, Tianli Tao, Chenchen Han, Yan He, Fengyuan Dai, Qingyan Yuan, Yuan Gao, Tong Si, Xuting Zhang and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Jin SuZhejiang University, Hangzhou, China.ORCID http://orcid.org/0009-0005-4021-9933
Zhikai LiWestlake University, Hangzhou, China.
Tianli TaoWestlake University, Hangzhou, China.
Chenchen HanWestlake University, Hangzhou, China.ORCID http://orcid.org/0000-0002-3330-5308
Yan HeWestlake University, Hangzhou, China.
Fengyuan DaiWestlake University, Hangzhou, China.
Qingyan YuanSuzhou Polynovo Biotech Co., Ltd., Suzhou, China.
Yuan GaoShenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Tong SiShenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID http://orcid.org/0000-0003-2985-9014
Xuting ZhangWestlake University, Hangzhou, China.ORCID http://orcid.org/0009-0007-9729-7347
Yuyang ZhouWestlake University, Hangzhou, China.
Junjie ShanWestlake University, Hangzhou, China.
Xibin ZhouWestlake University, Hangzhou, China.ORCID http://orcid.org/0009-0007-8879-4966
Xing ChangWestlake University, Hangzhou, China.ORCID http://orcid.org/0000-0002-5072-9225
Shiyu JiangWestlake University, Hangzhou, China.
Dacheng MaZhejiang Lab, Hangzhou, China.
OPMC
Martin SteineggerSchool of Biological Sciences, Seoul National University, Seoul, South Korea.ORCID http://orcid.org/0000-0001-8781-9753
Sergey OvchinnikovMassachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-2774-2744
Fajie YuanWestlake University, Hangzhou, China. yuanfajie@westlake.edu.cn.ORCID http://orcid.org/0000-0001-8452-9929

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Training and deploying large-scale protein language models typically requires deep machine learning expertise-a barrier for researchers outside this field. SaprotHub overcomes this challenge by offering an intuitive platform that facilitates training and prediction as well as storage and sharing of models. Here we provide the ColabSaprot framework built on Google Colab, which potentially powers hundreds of protein training and prediction applications, enabling researchers to collaboratively build and share customized models.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.