Evidence map›Paper›PMID 41136719›Full record

SynthesisDigestive diseases and sciences2026

Submucosal Tunneling Endoscopic Resection Versus Endoscopic Submucosal Dissection for Esophageal Submucosal Tumors: A Meta-Analysis.

Jia-Huan Liu, Li Tang, Qing Lu, Xiu-He Lv, Jin-Lin Yang

Abstract readMeta-AnalysisComparative StudySystematic Review
PubMed Publisher
In one paragraph

Synthesis in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jia-Huan Liu *Department of Gastroenterology and Hepatology, West China Hospital of Sichuan University, 37 Guo Xue Lane, Chengdu, 610041, Sichuan, China.
Li Tang *Department of Gastroenterology and Hepatology, West China Hospital of Sichuan University, 37 Guo Xue Lane, Chengdu, 610041, Sichuan, China.
Qing LuDepartment of Gastroenterology and Hepatology, West China Hospital of Sichuan University, 37 Guo Xue Lane, Chengdu, 610041, Sichuan, China.
Xiu-He LvDepartment of Gastroenterology and Hepatology, West China Hospital of Sichuan University, 37 Guo Xue Lane, Chengdu, 610041, Sichuan, China. lvxiuhe@wchscu.cn.
Jin-Lin YangDepartment of Gastroenterology and Hepatology, West China Hospital of Sichuan University, 37 Guo Xue Lane, Chengdu, 610041, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubmucosal tunneling endoscopic resection (STER) has emerged as a novel endoscopic technique for the treatment of esophageal submucosal tumors (SMTs). This meta-analysis aimed to compare the efficacy and safety of STER with endoscopic submucosal dissection (ESD) for managing esophageal SMTs.

methodsA literature search was conducted in PubMed, Embase, and the Cochrane Library through March 11, 2025, to identify comparative studies of STER and ESD. Primary outcomes included complete resection (CR) rate, en bloc resection (ER) rate, length of hospital stay (LOS), and operation time. Secondary outcomes were complication rates and tumor recurrence. Risk of bias and publication bias were assessed for all primary outcomes.

resultsSix comparative studies were included. There were no significant differences between STER and ESD in terms of CR rate (Risk Ratio [RR] 1.02; 95% Confidence Interval [CI] 0.91 to 1.14; I

conclusionBoth STER and ESD are effective and safe techniques for the resection of esophageal SMTs. However, STER is associated with a significantly shorter hospital stay.

Indexed as

Endoscopic Mucosal ResectionEsophageal NeoplasmsEsophagoscopyEsophageal MucosaHumansLength of StayOperative TimeTreatment OutcomeEndoscopic submucosal dissectionEsophageal submucosal tumorSubmucosal tunneling endoscopic resection

Identifiers

PMID41136719

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.