Evidence map›Paper›PMID 41136636›Full record

ArticleScientific reports2025

In vitro bioactivities and formulation stability of Houttuynia cordata essential oil for cosmetic applications.

Sarita Sangthong, Phanuphong Chaiwut, Punyawatt Pintathong, Benjarat Suwannawong, Montra Srisayam, Tinnakorn Theansungnoen, Kasemsiri Chandarajoti, Hesamoddin Arabnozari, Satyajit D Sarker, Lutfun Nahar

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sarita SangthongSchool of Cosmetic Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
Phanuphong ChaiwutSchool of Cosmetic Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
Punyawatt PintathongSchool of Cosmetic Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
Benjarat SuwannawongGreen Cosmetic Technology Research Group, School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
Montra SrisayamFaculty of Science and Technology, Pibulsongkram Rajabhat University, Phitsanulok, 65000, Thailand.
Tinnakorn TheansungnoenSchool of Cosmetic Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
Kasemsiri ChandarajotiDepartment of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, 90110, Songkhla, Thailand.
Hesamoddin ArabnozariMedicinal Plants Research Centre, Institute of Herbal Medicines and Metabolic Disorders, Mazandaran University of Medical Sciences, Sari, Iran. hesamarabnozari@yahoo.com.
Satyajit D SarkerCentre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool, L3 3AF, UK.
Lutfun NaharLaboratory of Growth Regulators, Institute of Experimental Botany, Palacký University, The Czech Academy of Sciences, Šlechtitelů 27, Olomouc, Czech Republic. profnahar@outlook.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Houttuynia cordata essential oil (HCEO) is a promising ingredient for acne-focused phytocosmetics. This in vitro study evaluated its volatile compounds, antimicrobial, antioxidant, wound-healing, anti-melanogenic, and anti-inflammatory properties, along with the stability of topical oil‑in‑water emulsions. GC-MS analysis identified n-decanoic acid (46.21%), β-myrcene (14.082%), and 2-undecanone (11.01%) as the main components. HCEO inhibited the growth of Staphylococcus aureus, Candida albicans, Staphylococcus epidermidis, and Cutibacterium acnes. It displayed antioxidant activity, with IC

Indexed as

CosmeticsHouttuyniaOils, VolatileAnimalsAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsCandida albicansHumansMiceNIH 3T3 CellsRAW 264.7 CellsWound HealingAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsCosmeticsOils, VolatileAnti-melanogenesisAntimicrobialAntioxidantHouttuynia cordata essential oilPhytocosmeticsWound healing

Identifiers

PMID41136636
PMCPMC12552693

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.