SynthesisScientific reports2025
Zoonotic brugian filariasis past and present trends in malaysia: A systematic review and proportionate meta-analysis.
Synthesis in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between BK polyomavirus and prostate cancer: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Mosquito vectors of lymphatic and zoonotic filariasis in Malaysia: a systematic review and proportionate meta-analysis of infection rates.Tropical medicine and health · 2026Review
- Challenges to 'Last Mile' Surveillance: Result of Programmatic Review of Integrated Skin NTDs Surveillance in Three Indonesian Districts.Tropical medicine and infectious disease · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Lymphatic filariasis is a neglected tropical disease of public health concern targeted for elimination globally. Malaysia is endemic to filariasis caused mainly by the filarial parasite Brugia malayi, with decades of continues elimination efforts. Despite recorded success, the disease is yet to be eliminated. Recently, reinfection in regions following mass drug administration programs and resurgence in some parts of the country raises concern as the country geared towards the 2030 filariasis elimination target. This study aims to provide pool prevalence estimates of the disease in animals and humans in Malaysia using a proportionate meta-analysis. Recent epidemiolocal data, potential filaria hotspots and the role of human induced environmental degradation on zoonotic filariasis transmission are also discussed. A Generalized Linear Mixed Model (GLMM) was used for the proportionate meta-analysis of prevalence data from 12 included studies. The result reveals overall human zoonotic filariasis estimated pool prevalence of 3% [95% CI: 0.01-0.09] and 5% [95% CI = 0.01-0.17] among animals in Malaysia, with a significant between study heterogeneity (I² = 97%; I² = 94%, p < 0.001, respectively). A subgroup meta-analysis of animal prevalence reveals high common effect estimated prevalence among monkeys 50% [95% CI = 0.43-0.58] with a random effect of 9% [0.00-0.94], with no observed between study heterogeneity (I² = 0%, p = 1). This study provides insight into zoonotic brugian filariasis that can be useful for the development of effective and sustainable lymphatic filariasis elimination program in Malaysia and other filarial endemic regions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.