SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026
Efficacy of endoscopic sinus surgery for chronic rhinosinusitis: a systematic review of systematic reviews.
Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeEndoscopic sinus surgery (ESS) is commonly performed to improve sinonasal complaints and enhance quality of life (QoL) for patients with chronic rhinosinusitis (CRS). Significant research has been published examining the efficacy of ESS in various domains that encompass CRS.
methodsA systematic search of PubMed, Web of Science, and Cochrane Central Register of Controlled Trials (CENTRAL) electronic databases was conducted. The review was performed following the PRISMA guidelines. Systematic reviews with or without meta-analyses (SRMA) investigating the efficacy of ESS in CRS patients were retrieved. All other study designs were excluded. A qualitative review of the published literature was performed.
resultsA total of 55 SRMAs met the final inclusion criteria. Most studies examined outcomes through patient reported outcome measures (PROM) such as the sinonasal outcome test (SNOT). Ten studies investigated the efficacy of ESS in comorbid conditions such as asthma or aspirin exacerbated respiratory disease (AERD). The remaining studies evaluated the role of intraoperative adjuncts, perioperative treatments, or the timing or extent of surgery.
conclusionsESS has significant, broad, and long-lasting positive impacts on a host of sinonasal domains. This systematic review of systematic reviews demonstrates the current breadth of research examining the efficacy of ESS for patients with CRS. Continued high quality research will improve outcomes and advance discovery.
Indexed as
Identifiers
41136564What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.