Targeting Pollutants in the Treatment and Prevention of Atopic Dermatitis.

Nadia Shobnam, Ian A Myles

Abstract readReview

In one paragraph

Review in Immunology and allergy clinics of North America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nadia ShobnamEpithelial Therapeutics Division, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA.

Ian A MylesEpithelial Therapeutics Division, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Building 10, Room 11N224, Bethesda, MD 20892, USA. Electronic address: mylesi@niaid.nih.gov.

Funding

Intramural NIH HHS Z99 AI999999

6 · The paper itself

Abstract

Mounting evidence suggests atopic dermatitis (AD) is primarily mediated by environmental exposures. This article focuses on specific air pollutants such as isocyanates and those in the benzene, toluene, ethylbenzene, and xylene family. We discuss the current strength and limitations of the data linking air pollution to AD. Brief mention is given to dietary and water-borne factors of concern. The proposed mechanisms of pathology for these chemicals are detailed. Finally, mitigation strategies are discussed with a focus on facilitating discussion between providers and patients related to the ways of improving AD without a prescription.

Indexed as

Air PollutantsDermatitis, AtopicEnvironmental ExposureHumansAir PollutantsAtopic dermatitisBTEXCeramidesIsocyanatePollution

Identifiers

PMID41136090

DOI10.1016/j.iac.2025.06.002

PMCPMC12552779

What OpenQuestion holds

Textmetadata

LicenceTDM

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.