ArticleJACC. Case reports2025
Rescue of Acute VSD in Takotsubo Cardiomyopathy: The Role of BiPella Support in High-Risk Recovery.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
backgroundTakotsubo cardiomyopathy (TTC) mimics acute coronary syndrome but typically occurs without obstructive coronary disease. Rare complications such as acute ventricular septal defect (VSD) carry a poor prognosis. CASE SUMMARY: An 83-year-old woman with multiple comorbidities presented with chest pain and dyspnea. Suspected ST-segment elevation myocardial infarction led to coronary angiography, which confirmed TTC with acute VSD. Echocardiography revealed VSD and reduced ejection fraction (30%-35%). An Impella CP device (Abiomed) was placed within 2 hours, and urgent surgical VSD repair was performed within 32 hours. Postoperatively, BiPella (biventricular Impella) support optimized biventricular unloading. DISCUSSION: Acute VSD in TTC is rare and often fatal. Early mechanical circulatory support can stabilize patients and improve surgical outcomes. This case highlights the importance of prompt intervention in TTC-related VSD. TAKE-HOME MESSAGE: Early mechanical support and timely surgical intervention in TTC with VSD can be lifesaving and improve outcomes.
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