Evidence map›Paper›PMID 41136041›Full record

ArticleJACC. Case reports2025

How to Manage Double Obstructions: Stories of Aortic and Mitral Stenosis.

Vyanne Hei-Tung Chan, Ling-Na Wong, Kevin Ka-Ho Kam, Simon Chi-Ying Chow, Linda M L Lai, Albert Kam-Ming Chan, Randolph H L Wong, Alex Pui-Wai Lee, Kent Chak-Yu So

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vyanne Hei-Tung ChanDivision of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Ma Liu Shui, Hong Kong SAR, China.
Ling-Na WongDivision of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Ma Liu Shui, Hong Kong SAR, China.
Kevin Ka-Ho KamDivision of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Ma Liu Shui, Hong Kong SAR, China.
Simon Chi-Ying ChowDivision of Cardiothoracic Surgery, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Ma Liu Shui, Hong Kong SAR, China.
Linda M L LaiDepartment of Anaesthesia and Intensive Care, Prince of Wales Hospital, Chinese University of Hong Kong, Ma Liu Shui, Hong Kong SAR, China.
Albert Kam-Ming ChanDepartment of Anaesthesia and Intensive Care, Prince of Wales Hospital, Chinese University of Hong Kong, Ma Liu Shui, Hong Kong SAR, China.
Randolph H L WongDivision of Cardiothoracic Surgery, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Ma Liu Shui, Hong Kong SAR, China.
Alex Pui-Wai LeeDivision of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Ma Liu Shui, Hong Kong SAR, China.
Kent Chak-Yu SoDivision of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Ma Liu Shui, Hong Kong SAR, China. Electronic address: kentso987@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multivalvular disease presents unique clinical challenges compared with isolated valve pathologies because they often involve altered hemodynamics and physiology. A common combination is aortic stenosis and mitral stenosis, which frequently coexist owing to rheumatic or degenerative etiologies. This case series explores 3 patients with concurrent severe symptomatic mitral stenosis and aortic stenosis, illustrating how management strategies can vary significantly based on the patient's surgical risk, symptom burden, and anatomical features. These cases illustrate the experiences at our institution in managing patients with double obstructions, and they emphasize the importance of accurate assessment of disease severity as well as the need for tailored interventional strategies. They highlight the gap in international guidelines for managing such complex multivalvular pathologies and underscore the necessity of a more structured and comprehensive approach to optimize patient outcomes.

Indexed as

aortic stenosismitral stenosismultivalvular diseasevalvular heart disease

Identifiers

PMID41136041
PMCPMC12789794

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.