Evidence map›Paper›PMID 41136037›Full record

ArticleJACC. Case reports2025

Acute Hemodynamic Instability After Transcatheter Tricuspid Valve Replacement.

Robin Le Ruz, Daniel Burkhoff, Isaac George, Karl-Philipp Rommel, Michael I Brener, Martin B Leon, Susheel K Kodali, Rebecca T Hahn

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Robin Le RuzNantes Université, CHU Nantes, Interventional Cardiology Department, l'institut du thorax, Nantes, France; Nantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France; Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA. Electronic address: robin.leruz@chu-nantes.fr.
Daniel BurkhoffCardiovascular Research Foundation, New York, New York, USA.
Isaac GeorgeDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Karl-Philipp RommelDepartment of Cardiology, Cardiology I, University Medical Center Mainz, Mainz, Germany.
Michael I BrenerDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Martin B LeonDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Susheel K KodaliDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Rebecca T HahnDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.

Funding

Predicting the hemodynamic response to mitral valve interventions with pressure-volume analysisK23HL177311 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Michael Brener · 2025 to 2026
$346k
NHLBI NIH HHS K23 HL177311
6 · The paper itself

Abstract

We describe a series of 3 patients presenting with acute hemodynamic instability (AHI) after transcatheter tricuspid valve replacement (TTVR). The first case illustrates abrupt right ventricular-pulmonary artery uncoupling due to the marked increase in afterload that stereotypically occurs after acute reduction of tricuspid regurgitation. The second case illustrates AHI after myocardial ischemia triggered by TTVR in a patient with infiltrative cardiomyopathy. The third case highlights AHI as a consequence of marked vasoplegia precipitated by a robust, unregulated inflammatory response after TTVR. Although AHI after TTVR is infrequent, the condition is highly morbid, and prompt recognition of the underlying cause is essential to stabilize the patient and facilitate recovery. We also illustrate the potential for using a cardiac simulator to predict the hemodynamic consequences of TTVR. Development of novel predictive tools and familiarity with the clinical patterns of AHI after TTVR will become increasingly important as TTVR becomes more common.

Indexed as

chronic heart failurestructural heart diseasestructural interventiontricuspid regurgitation

Identifiers

PMID41136037
PMCPMC12789826

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.