Evidence map›Paper›PMID 41135948›Full record

ReviewJournal for immunotherapy of cancer2025

Role of cDC2 in priming CD8

Ahmed E I Hamouda, Damya Laoui

Abstract readReview
In one paragraph

Review in Journal for immunotherapy of cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ahmed E I HamoudaLab of Dendritic Cell Biology and Cancer Immunotherapy, VIB Center for Inflammation Research, Brussels, Belgium.ORCID http://orcid.org/0000-0001-6532-9585
Damya LaouiLab of Dendritic Cell Biology and Cancer Immunotherapy, VIB Center for Inflammation Research, Brussels, Belgium dlaoui@vub.be.ORCID http://orcid.org/0000-0002-3373-1403

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 conventional dendritic cell (cDC2) gene signature was shown to be associated with better overall survival in patients with lung cancer and a fraction of patients with breast carcinoma, indicating that they may possess antitumoral function. Nevertheless, unraveling the antitumoral role of cDC2s proved to be challenging due to their complex development and heterogeneity. Here, we discuss findings showcasing the ability of cDC2s to prime cytotoxic CD8

Indexed as

CD8-Positive T-LymphocytesDendritic CellsNeoplasmsAnimalsHumansLymphocyte ActivationDendriticTumor microenvironment - TME

Identifiers

PMID41135948
PMCPMC12557737

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.