Evidence map›Paper›PMID 41135848›Full record

ReviewThe American journal of the medical sciences2026

Update on Influenza.

Alisse Hannaford, Muneerah Aleissa, Amy C Sherman

Abstract readReview
In one paragraph

Review in The American journal of the medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alisse HannafordDivision of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, USA; Dana-Farber Cancer Institute, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA.
Muneerah AleissaCollege of Pharmacy, Department of Pharmacy Practice, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Amy C ShermanDivision of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, USA; Dana-Farber Cancer Institute, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA. Electronic address: acsherman@bwh.harvard.edu.

Funding

INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
Defining vaccine immunogenicity and adoptive transfer in hematopoietic stem cell transplant recipientsK23AI185318 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Amy Caryn Sherman · 2025 to 2026
$389k
NIAID NIH HHS K23 AI185318NIAID NIH HHS T32 AI007061
6 · The paper itself

Abstract

Influenza continues to challenge global health systems due to its evolving clinical and epidemiological features, with significant morbidity and mortality worldwide. Vaccine development remains a cornerstone of prevention, with attention to annual strain selection and enhanced formulations such as adjuvanted, high-dose, and recombinant vaccines. Promising innovations on the horizon include next-generation influenza vaccines, multi-pathogen vaccines, and universal influenza vaccines, with new technologies employing mRNA platforms and alternative vaccine administration strategies. The role of antivirals for prophylaxis and treatment are evaluated, including synergistic effects and resistance trends. Considerations for vulnerable populations with increased risk are highlighted. This review provides a timely synthesis of current knowledge and emerging strategies in diagnostics, therapeutics, and prevention to strengthen clinical outcomes and public health responses to influenza in the United States.

Indexed as

Influenza, HumanInfluenza VaccinesAntiviral AgentsHumansUnited StatesAntiviral AgentsInfluenza VaccinesInfectious diseaseInfluenzaPharmacology

Identifiers

PMID41135848
PMCPMC12750516

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.