Evidence map›Paper›PMID 41135255›Full record

ArticleSocial science & medicine (1982)2025

The stakes of stimulant use, psychosis, and antipsychotic treatment among youth who use drugs: A longitudinal qualitative study.

Trevor Goodyear, Madison Thulien, Alexandra Anghel, Allie Slemon, Mazal Jensen, Martha J Ignaszewski, Roberto Sassi, Steve Mathias, Emily Jenkins, Rod Knight and 1 more

Abstract read
In one paragraph

Article in Social science & medicine (1982), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Trevor GoodyearSchool of Nursing, University of British Columbia, Vancouver, BC, Canada; Wellstream: The Canadian Centre for Innovation in Child and Youth Mental Health, Vancouver, BC, Canada; Human Early Learning Partnership, School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.
Madison ThulienYouth Health Research Program, British Columbia Centre on Substance Use, Vancouver, BC, Canada.
Alexandra AnghelDepartment of Psychiatry, University of British Columbia, Vancouver, BC, Canada; Department of Psychiatry, St Paul's Hospital, Vancouver, BC, Canada.
Allie SlemonSchool of Nursing, University of Victoria, Victoria, BC, Canada.
Mazal JensenYouth Health Research Program, British Columbia Centre on Substance Use, Vancouver, BC, Canada.
Martha J IgnaszewskiDepartment of Psychiatry, University of British Columbia, Vancouver, BC, Canada.
Roberto SassiDepartment of Psychiatry, St Paul's Hospital, Vancouver, BC, Canada; British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
Steve MathiasDepartment of Psychiatry, University of British Columbia, Vancouver, BC, Canada; Foundry, Vancouver, BC, Canada.
Emily JenkinsSchool of Nursing, University of British Columbia, Vancouver, BC, Canada; Wellstream: The Canadian Centre for Innovation in Child and Youth Mental Health, Vancouver, BC, Canada; Human Early Learning Partnership, School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.
Rod KnightÉcole de Santé Publique, Université de Montréal, Montréal, QC, Canada; Centre de Recherche en Santé Publique (CReSP), Montréal, QC, Canada.
Danya FastBritish Columbia Children's Hospital Research Institute, Vancouver, BC, Canada; Foundry, Vancouver, BC, Canada; Department of Medicine, University of British Columbia, Vancouver, BC, Canada. Electronic address: danya.fast@ubc.ca.

Funding

An ethno-epidemiological study of the implementation and effectiveness of an innovative and comprehensive response to the opioid epidemicR01DA044181 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI Thomas Kerr, Ryan McNeil · 2017 to 2026
$4.0M
NIDA NIH HHS R01 DA044181
6 · The paper itself

Abstract

Psychosis among youth who use drugs in the context of entrenched poverty is often addressed through aggressive forms of psychiatric intervention. Clinicians must carefully consider the benefits and drawbacks of this approach with this population because of how institutionalization and the sedating and numbing effects and affects of antipsychotics may be distinctly constraining. This study aims to increase understanding of the benefits, drawbacks, and socio-material and political contexts of antipsychotic treatment for youth who use drugs. We draw on in-depth, longitudinal qualitative interviews conducted between 2018 and 2021 with 116 youth who used drugs while contending with entrenched poverty in Metro Vancouver, Canada. Our analysis leverages a reflexive thematic approach and ideas from critical psychiatry and mad studies. We begin by outlining a 'psychopolitical landscape' wherein youth could become swept up in mental health certification and antipsychotic treatment with particular and oftentimes negative effects and affects. We then explore how, in the constant shadow of this psychopolitical landscape and socio-material deprivation, youth often sought to balance slippages away from and toward more stable senses of reality engendered by regular stimulant use. Finally, we examine how young people's lived experiences of stimulant use and psychosis shaped their psychiatric treatment trajectories, including through dynamics of refusal, self-management, and performed sanity under the gaze of the psychopolitical landscape. From these findings, we underscore the need to prioritize self-determination - as much as is possible and safe - and equity-focused approaches that address the socio-material conditions of youths' lives in mental health and substance use care. Providers should continually open conversations with youth about lived realities of substance use and psychosis alongside broader desires for the future, finding ways of working with youth within and beyond psychiatric treatment.

Indexed as

Antipsychotic AgentsCentral Nervous System StimulantsPsychotic DisordersSubstance-Related DisordersAdolescentBritish ColumbiaCanadaFemaleHumansLongitudinal StudiesMalePovertyQualitative ResearchYoung AdultAntipsychotic AgentsCentral Nervous System StimulantsAntipsychoticHomelessnessMental healthPsychosisSubstance useTreatmentYouth

Identifiers

PMID41135255
PMCPMC13064883

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.