Evidence map›Paper›PMID 41135124›Full record

ArticleAddictive behaviors2026

A longitudinal mediated examination of legal, commercial, and individual determinants of cannabis and derived cannabis use behaviors and consequences among US young adults.

Cassidy R LoParco, Matthew E Rossheim, Yan Wang, Y Tony Yang, Nino Paichadze, Patricia A Cavazos-Rehg, Carla J Berg

Abstract read
In one paragraph

Article in Addictive behaviors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cassidy R LoParcoDepartment of Prevention and Community Health, Milken Institute School of Public Health, the George Washington University, Washington, DC, USA. Electronic address: Cassidy.LoParco@gwu.edu.
Matthew E RossheimDepartment of Health Administration and Health Policy, College of Public Health, University of North Texas Health Science Center, Fort Worth, TX, USA.
Yan WangDepartment of Prevention and Community Health, Milken Institute School of Public Health, the George Washington University, Washington, DC, USA; George Washington Cancer Center, the George Washington University, Washington, DC, USA.
Y Tony YangGeorge Washington Cancer Center, the George Washington University, Washington, DC, USA; Department of Health Policy and Media Engagement, School of Nursing, the George Washington University, Washington, DC, USA.
Nino PaichadzeDepartment of Global Health, Milken Institute School of Public Health, the George Washington University, Washington, DC, USA.
Patricia A Cavazos-RehgDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Carla J BergDepartment of Prevention and Community Health, Milken Institute School of Public Health, the George Washington University, Washington, DC, USA; George Washington Cancer Center, the George Washington University, Washington, DC, USA.

Funding

Recreational Marijuana Marketing and Young Adult Consumer Behavior - Administrative SupplementR01DA054751 · NIDA · GEORGE WASHINGTON UNIVERSITY · PI Carla J Berg, Patricia A Cavazos-Rehg · 2022 to 2026
$4.3M
Socio-structural determinants of cannabis and derived psychoactive cannabis product use and consequences among young adultsF32DA060612 · NIDA · GEORGE WASHINGTON UNIVERSITY · PI LOPARCO, CASSIDY R · 2024 to 2025
$101k
NIDA NIH HHS F32 DA060612NIDA NIH HHS R01 DA054751
6 · The paper itself

Abstract

backgroundCannabis and derived intoxicating cannabis product (DICP; e.g., delta-8 tetrahydrocannabinol [THC]) use is increasing, particularly among young adults. We examined how state cannabis and DICP laws and cannabis advertisement exposure impact cannabis/DICP risk perceptions and use motives and how those, in turn, impact cannabis and DICP behaviors (use, frequency, intentions) and consequences.

methodsWe analyzed two waves (2023-2024) of longitudinal survey data among 3,437 US young adults ages 18-34 (∼50 % past-month cannabis use by design). Multivariable regressions assessed direct and indirect associations via parallel mediation.

resultsParticipants in states with legal (vs. illegal) non-medical cannabis had lower DICP use motives, higher odds of cannabis-only use (vs. neither or both), and used cannabis more frequently; associations with use behaviors were mediated by cannabis/DICP motives and risk perceptions. More restrictive delta-8 THC laws were associated with higher odds of cannabis-only use (vs. neither or both). More digital cannabis ad exposure and less exposure to traditional/store-based ads were associated with lower risk perceptions and higher use motives, odds of cannabis/DICP use, use intentions, and consequences; associations were mediated by cannabis/DICP use motives and/or risk perceptions. Lower cannabis/DICP risk perceptions and higher use motives were associated with higher odds of using each respective substance, co-use, and intentions. Using cannabis/DICPs more frequently was associated with experiencing more cannabis consequences; cannabis/DICP frequency mediated associations of cannabis state laws, advertising exposure, and motives with cannabis consequences.

conclusionsThese pathways underscore how laws and marketing shape use, supporting interventions targeting risk perceptions and motives to reduce harm.

Indexed as

Marijuana SmokingMarijuana UseAdolescentAdultAdvertisingCannabisFemaleHumansIntentionLongitudinal StudiesMaleMotivationUnited StatesYoung AdultCannabisConsequencesDelta-8MarketingPolicyRisk perceptionsUse motives

Identifiers

PMID41135124
PMCPMC12704332

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.