Evidence map›Paper›PMID 41134977›Full record

ReviewJournal of Alzheimer's disease : JAD2025

Air pollution and Alzheimer's disease prevention: The science and a prevention plan.

Dharma Singh Khalsa, Helen Lavretsky, Meghan Y Reddy, Annie Fenn, Christopher Walling

Abstract readReview
In one paragraph

Review in Journal of Alzheimer's disease : JAD, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dharma Singh KhalsaAlzheimer's Research and Prevention Foundation, Tucson, AZ, USA.ORCID 0000-0002-6373-5173
Helen LavretskyDepartment of Psychiatry & Biobehavioral Sciences, David Geffen School of Medicine at UCLA, and Semel Institute for Neuroscience and Behavior, UCLA, Los Angeles, CA, USA.
Meghan Y ReddyDepartment of Psychiatry & Biobehavioral Sciences, David Geffen School of Medicine at UCLA, and Semel Institute for Neuroscience and Behavior, UCLA, Los Angeles, CA, USA.
Annie FennPrivate practice and author, Wilson, WY, USA.
Christopher WallingDepartment of Research Psychology, California Institute of Integral Studies, San Francisco, CA, USA.ORCID 0000-0003-0175-1108

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Today, approximately 7.2 million people have Alzheimer's disease in the United States. That number is expected to double by 2060 if a preventive approach is not undertaken. Globally, those figures are also predicted to increase. As we'll soon discover, air pollution and other aspects of climate change are a predominant cause of this remarkable surge. The purpose of this article is to examine the scientific basis of pollution and suggest that an evolutionary lifestyle medicine program may help mitigate and slow down its negative effects on brain health. This review examines existing literature on pollution, and lifestyle as well as other aspects of a lifestyle medicine program, including diet, exercise, stress reduction especially via yoga and meditation, good sleep and essential and spiritual well-being, thus investigating their potential to enhance awareness of the issue and prevent the increase in Alzheimer's disease predicted to arise from air pollution and other forms of climate stress. Air pollution, and the potential for global warming, presents a critical emergency. Scientific evidence indicates that these factors contribute to an elevated risk of Alzheimer's disease, along with other neurological, mental, and physical health challenges. Our hypothesis is that an evidence-based lifestyle medicine program can potentially prevent, slow, or reverse multiple medical problems that are tied to Alzheimer's disease prevention. It is hypothesized that once practitioners of this program become aware, they can reach out to their family, friends, communities, country and globally to attend to the issue with strength, wisdom and clarity.

Indexed as

Air PollutionAlzheimer DiseaseHealthy LifestylePrimary PreventionClimate ChangeGlobal HealthHumansAlzheimer's diseaseenvironmental pollutionessential well-beingexerciselifestyle medicinemeditationnutritionpreventionspiritual fitnessyoga

Identifiers

PMID41134977
PMCPMC12647382

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.