Evidence map›Paper›PMID 41134683›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2025

Pulmonary function responses to extreme heat exposure in younger and older adults.

Elizabeth A Gideon, Zachary J McKenna, Josh Foster, Whitley C Atkins, Taysom E Wallace, Bryce N Balmain, Andrew R Tomlinson, Tony G Babb, Craig G Crandall

Abstract readComparative Study
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elizabeth A GideonInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0009-0002-6877-681X
Zachary J McKennaInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0003-2502-8870
Josh FosterInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0001-6232-9336
Whitley C AtkinsInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0003-1610-048X
Taysom E WallaceInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0009-0004-6002-778X
Bryce N BalmainInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0002-2642-7083
Andrew R TomlinsonInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0001-9899-0812
Tony G BabbInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0002-0515-2164
Craig G CrandallInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0001-7792-9713

Funding

TRAINING PROGRAM IN LUNG BIOLOGY AND DISEASET32HL098040 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SHAUL, PHILIP W, TERADA, LANCE S · 2009 to 2024
$4.6M
Heat waves and the elderly: reducing thermal and cardiovascular consequencesR01AG069005 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI CRANDALL, CRAIG G · 2021 to 2025
$2.8M
Low-energy cooling strategies to reduce the thermal, cardiovascular, and renal consequences of heat waves in the elderly.F32HL168826 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI MCKENNA, ZACHARY JOHN · 2024 to 2025
$149k
American Heart Association (AHA) 23POST1023065American Heart Association (AHA) 24POST1192222American Heart Association-American Stroke Association 23POST1023065HHS | National Institutes of Health (NIH) F32HL168826HHS | National Institutes of Health (NIH) R01AG069005HHS | National Institutes of Health (NIH) T32HL098040NHLBI NIH HHS F32 HL168826NHLBI NIH HHS T32 HL098040NIA NIH HHS R01 AG069005
6 · The paper itself

Abstract

Older adults have both lower pulmonary function and impaired thermoregulation compared with younger adults. In addition, epidemiological evidence suggests that extreme heat exposure increases the incidence of pulmonary complications in older adults. However, the impact of extreme heat exposure on pulmonary function in healthy older and younger adults is not well described. To assess this question, spirometry was performed at baseline in a thermoneutral environment and at the end of a 3-h heat exposure in a DRY (47°C and 15% humidity) and HUMID (41°C and 40% humidity) environment. Fifteen younger (7 female; 30 ± 5 yr) and 15 older (8 female; 72 ± 5 yr) adults completed the study. In the DRY condition, the younger adults had no change in forced vital capacity (FVC) from baseline (4.34 ± 0.55 L) to end-heating (4.31 ± 0.62 L;

Indexed as

AgingExtreme HeatLungAdultAgedAge FactorsBody Temperature RegulationFemaleForced Expiratory VolumeHot TemperatureHumansHumidityMaleSpirometryVital CapacityYoung Adultagingspirometrytemperature

Identifiers

PMID41134683
PMCPMC12581803

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.