Observational studyInterdisciplinary cardiovascular and thoracic surgery2025
Perioperative Veno-Venous Extracorporeal Membrane Oxygenation in Non-Elective Thoracic Surgery: A Propensity-Matched Bicentric Comparison With Medical Indication.
Observational study in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07016685 (Prognostic Factors for 90-day Mortality in Patients Undergoing Veno-venous Extracorporeal Membrane Oxygenation for Emergency Thoracic Surgery), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prognostic Factors for 90-day Mortality in Patients Undergoing Veno-venous Extracorporeal Membrane Oxygenation for Emergency Thoracic Surgery
Who cites it
1 citing paper in PubMed.
- Safety of Invasive Procedures During Adult Extracorporeal Membrane Oxygenation: A Systematic Review.Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPerioperative veno-venous extracorporeal membrane oxygenation (VV-ECMO) can be used during non-elective thoracic surgery to manage hypoxaemia and facilitate complex surgical procedures. However, outcome data in this setting remain limited, particularly regarding bleeding and thrombotic risks. We aimed to evaluate whether perioperative VV-ECMO during non-elective thoracic surgery is associated with increased 90-day all-cause mortality compared with VV-ECMO used for medical indications, using a propensity score-matched analysis. Secondary outcomes included major bleeding and thrombotic events.
methodsThis retrospective bi-centre cohort study included adults treated with VV-ECMO for acute respiratory failure between January 2011 and January 2025 in 2 university intensive care units. Patients were categorized according to ECMO indication: perioperative thoracic surgery or medical. A propensity score was built using multivariable logistic regression, followed by 1:4 nearest-neighbor matching without replacement. The primary endpoint was 90-day mortality; secondary endpoints included major bleeding and thrombotic events.
resultsAmong 372 patients, 44 (12%) received perioperative VV-ECMO. Ventilator-associated pneumonia (78% vs 57%, P = .01) and haemothorax (36% vs 2%, P < .001) were more frequent in the perioperative group. Ninety-day mortality did not differ between groups, both before (54% vs 51%, P = .71) and after matching (log-rank P = .95). Multivariable Cox analysis confirmed no association between surgical ECMO and mortality (HR = 1.003, 95% CI [0.64-1.57]). No significant differences were found in major bleeding (48% vs 47%, P = 1.00) or thrombotic events (41% vs 32%, P = .31) between groups.
conclusionsPerioperative VV-ECMO during non-elective thoracic surgery was not associated with increased 90-day mortality, bleeding, or thrombotic complications compared to medical VV-ECMO, both before and after matching. These findings support its use in carefully selected patients. CLINICAL TRIAL REGISTRATION NUMBER: NCT07016685.
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