Evidence map›Paper›PMID 41134547›Full record

ArticleJournal of applied clinical medical physics2025

Hemodialysis-associated radioactive waste management in [

Dennis Kupitz, Heiko Wissel, Martin Volk, Michael C Kreissl, Oliver S Grosser

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Hemodialysis-associated radioactive waste management in [Journal of applied clinical medical physics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dennis KupitzDepartment for Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany.ORCID https://orcid.org/0000-0003-0761-4964
Heiko WisselDepartment for Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany.ORCID https://orcid.org/0000-0001-7664-4900
Martin VolkDepartment for Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany.ORCID https://orcid.org/0000-0003-0367-4628
Michael C KreisslDepartment for Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany.ORCID https://orcid.org/0000-0001-5905-6015
Oliver S GrosserDepartment for Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany.ORCID https://orcid.org/0000-0002-0826-0734

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadionuclide therapy, such as with iodine-131 or lutetium-177-labeled substances, is used to treat thyroid cancer and neuroendocrine tumors. Due to the incorporated radioactivity, patients must remain hospitalized until radiation levels are deemed safe, according to national regulations. This is particularly problematic for patients who require hemodialysis (HD). While contamination of dialysis waste after radionuclide therapy is generally well recognized, a critical gap remains regarding its duration and extent. This poses risks for patient management and outpatient staff. PURPOSE: This study aims to demonstrate the problems with classifying residual waste and provides arguments for appropriate regulation. It evaluates if the radioactivity of the dialysate and residuals at discharge, based on whole-body measurements, complies with relevant limits. If not, the waste is classified as radioactive and treated accordingly.

methodsWe studied four patients treated by radionuclide therapy who required dialysis: three received [

resultsPatient 1 ([

conclusionsThis study highlights the need for refined monitoring and the limitations of standard discharge strategies for patients requiring dialysis during radionuclide therapy. Even if dose limits are met, dialysate and residuals may still require regulated handling and storage.

Indexed as

Iodine RadioisotopesLutetiumNeuroendocrine TumorsOctreotideOrganometallic CompoundsRadioactive WasteRenal DialysisThyroid NeoplasmsWaste ManagementAgedFemaleHumansMaleMiddle AgedRadioisotopesRadiopharmaceuticalsIodine-131Iodine RadioisotopesLutetiumLutetium-177lutetium Lu 177 dotatateOctreotideOrganometallic CompoundsRadioactive WasteRadioisotopesRadiopharmaceuticalshemodialysisnuclear medicineradiation protectionradionuclide therapy

Identifiers

PMID41134547
PMCPMC12551593

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.