Evidence map›Paper›PMID 41134505›Full record

ArticleRice (New York, N.Y.)2025

Identification of MicroRNAs Involved in Different Layers of Rice-Magnaporthe oryzae Interaction.

Sadam Hussain Bhutto, Yong Zhu, Hao Su, Hao Xue, Xiao-Yu Xiong, Yuan Yang, Yun-Hao Zheng, Hong-Sen Deng, Si-Yao Zhang, De-Qiang Li and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Rice (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Wheat miR408 and miR159 Weaken the Virulence ofPlants (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Sadam Hussain Bhutto *State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Yong Zhu *State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Hao SuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Hao XueState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Xiao-Yu XiongState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Yuan YangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Yun-Hao ZhengState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Hong-Sen DengState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Si-Yao ZhangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
De-Qiang LiState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Xue-Mei YangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
He WangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Guo-Bang LiState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Zhi-Xue ZhaoState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Ji-Wei ZhangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Yan-Yan HuangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Muhammad Ibrahim KhaskheliState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Wen-Ming WangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China. j316wenmingwang@sicau.edu.cn.
Yan LiState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China. liyan_rice@sicau.edu.cn.

Funding

National Natural Science Foundation of China 32121003National Natural Science Foundation of China 32172417National Natural Science Foundation of China 32202263National Natural Science Foundation of China 32372553National Natural Science Foundation of China 32401845Open Research Fund of State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China SKL-ZD202202Open Research Fund of State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China SKL-ZY202202Open Research Fund of State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China SKL-ZY202205Open Research Fund of State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China SKL-ZY202209Science and Technology Department of Sichuan Province 2021YFYZ0021-4-2Science and Technology Department of Sichuan Province 2025ZNSFSC1115Science and Technology Department of Sichuan Province SCCXTD-2024-SD-4
6 · The paper itself

Abstract

Rice blast disease is one of the most destructive rice diseases worldwide. Rice MicroRNAs (miRNAs) play an essential role in immunity against blast fungus Magnaporthe oryzae. However, it remains unclear which miRNAs are involved in the three layers of rice-M. oryzae interaction, including pathogen associated molecular patterns (PAMPs)-triggered immunity (PTI), effector-triggered susceptibility (ETS), and effector-triggered immunity (ETI). In this study, we performed small RNA-sequencing to systemically identify miRNAs regulating PTI, ETS, and ETI in rice-M. oryzae interaction. A totally 441 miRNAs were identified, with 13, 30, and 14 miRNAs screened out and classified as regulators of PTI, ETS, and ETI, respectively. We investigated and confirmed the roles of 9 previously reported miRNAs and an uncharacterized miRNA, miR408-5p, in the three interaction processes. We demonstrated that miR1320-5p positively regulated PTI; miR396 family members and miR164a improved, whereas miR171b and miR172a suppressed ETS; miR166a enhanced, whereas miR169a and miR396 family members suppressed ETI. Moreover, we demonstrated that miR397b and miR408-5p enhanced rice susceptibility by promoting ETS and suppressing ETI; miR398b enhanced rice resistance by promoting both PTI and ETI while suppressing ETS. Our findings figured a miRNA-mediated regulatory network in which distinct miRNAs modulate PTI, ETS, and ETI against M. oryzae. This study provides new sight into the regulation mechanism of plant disease resistance.

Indexed as

ETIETSMagnaporthe oryzaeMiRNAsPTIRice blast diseaseSmall RNA-sequencing

Identifiers

PMID41134505
PMCPMC12552204

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.