ArticleClinical oral investigations2025
Evaluation of the effects on lower central incisors intrusion and lower first molar extrusion at different mixed dentition stages using clear aligners for deep overbite treatment: a retrospective study.
Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Pediatric mainstream clear-aligner early orthodontic orders in Guangdong public tertiary hospitals: service patterns, service-duration tiers and order conversion.BMC oral health · 2026Observational
- Clear aligner therapy: a scoping review of treatment prediction, clinical effectiveness, and limitations.Frontiers in dental medicine · 2026Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundDeep overbite, a prevalent malocclusion, may cause oral-maxillofacial dysfunction if untreated during mixed dentition. This study evaluated clear aligner efficacy for deep overbite correction across developmental stages of lower central incisors, assessing the accuracy of incisors intrusion and first molar extrusion alongside root development and alveolar bone height changes.
methods46 volunteers were selected as the Control groups. 38 patients were selected as the Treatment groups. The study analyzed changes in lower central incisors' intrusion amount, intrusion rate and labial inclination, lower first molars' extrusion amount, extrusion rate, bucco-lingual and mesial-distal inclination as well as the changes in root length, root apical foramen size and alveolar bone height before and after first batch of clear aligners.
resultsLower central incisors at stages F, G and H showed intrusion rates of 33.3%, 34.1% and 34.6%, while first molars at G, H-1 and H-2 demonstrated extrusion rates of 29.0%, 29.4% and 29.2%. Regardless of the root developmental stage, neither lower central incisors nor first molars exhibited statistically significant differences in root length, root apical foramen size, alveolar bone height compared to the Control groups (P > 0.05).
conclusionClear aligners could produce an intrusion effect on lower central incisors while achieving a slight extrusion of lower first molars during mixed dentition. In addition, the developing roots continued their normal progression in the treatment process. And no significant changes were observed in developed roots. Regardless of the developmental stages of roots, there were also no obvious changes in the alveolar bone height.
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Registered trials
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