Evidence map›Paper›PMID 41133978›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Synthesis of Primary Amines via Reductive Amination of Aldehydes and Ketones Over a Ni-Doped MFM-300(Cr) Catalyst.

Wenyuan Huang, Bing An, Zeyu Chen, Yu Han, Yinlin Chen, Jiangnan Li, Xue Han, Shaojun Xu, Danielle Crawshaw, Evan Tillotson and 9 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. MOF-Derived InNanomaterials (Basel, Switzerland) · 2026
    Article
  2. Cu/TiOMolecules (Basel, Switzerland) · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Wenyuan HuangCollege of Chemistry and Molecular Engineering, Beijing National Laboratory for Molecular Sciences, Peking University, Beijing, 100871, China.
Bing AnDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Zeyu ChenDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Yu HanDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Yinlin ChenDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Jiangnan LiCollege of Chemistry and Molecular Engineering, Beijing National Laboratory for Molecular Sciences, Peking University, Beijing, 100871, China.
Xue HanDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Shaojun XuDepartment of Chemical Engineering, University of Manchester, Manchester, M13 9PL, UK.
Danielle CrawshawDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
Evan TillotsonDepartment of Materials, University of Manchester, Manchester, M13 9PL, UK.
Bing HanDepartment of Materials, University of Manchester, Manchester, M13 9PL, UK.
Sarah J HaighDepartment of Materials, University of Manchester, Manchester, M13 9PL, UK.
Christopher M A ParlettDepartment of Chemical Engineering, University of Manchester, Manchester, M13 9PL, UK.
Luke KeenanDiamond Light Source, Harwell Science Campus, Oxfordshire, OX11 0DE, UK.
Svemir RudićISIS Facility, STFC Rutherford Appleton Laboratory, Oxfordshire, OX11 0AF, UK.
Yongqiang ChengNeutron Scattering Division, Neutron Sciences Directorate, Oak Ridge National Laboratory, Oak Ridge, TN, TN 37830, USA.
Ben F SpencerDepartment of Materials, University of Manchester, Manchester, M13 9PL, UK.
Martin SchröderDepartment of Chemistry, University of Manchester, Manchester, M13 9PL, UK.ORCID https://orcid.org/0000-0001-6992-0700
Sihai YangCollege of Chemistry and Molecular Engineering, Beijing National Laboratory for Molecular Sciences, Peking University, Beijing, 100871, China.

Funding

Engineering and Physical Sciences Research Council EP/I011870Engineering and Physical Sciences Research Council EP/V056409European Research Council 742401
6 · The paper itself

Abstract

The development of earth-abundant metal-based catalysts is an important goal for the synthesis of fine chemicals. Here, an active nickel catalyst supported on a robust metal-organic framework, MFM-300(Cr), is reported which shows an exceptional performance for reductive amination, a reaction that has long been dominated by noble metals. Ni/MFM-300(Cr) promotes the synthesis of 38 primary amines via reductive amination of their parent carbonyl compounds, including biomass-derived aldehydes and ketones, using NH

Indexed as

catalysisMOFneutron scatteringreductive aminationstructure

Identifiers

PMID41133978
PMCPMC12697848

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.