Evidence map›Paper›PMID 41133916›Full record

ArticleJournal of hospital medicine2026

Intravenous line-related outcomes by antibiotic route for children hospitalized with pneumonia.

Jillian M Cotter, Angela Dunn, Isabella Zaniletti, Kathryn Colborn, Derek J Williams, Sriram Ramgopal, Cristin Q Fritz, Maia Taft, Matthew Hall, Elizabeth Temte and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of hospital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jillian M CotterSection of Hospital Medicine, Department of Pediatrics, Children's Hospital Colorado, University of Colorado, Aurora, Colorado, USA.ORCID https://orcid.org/0000-0002-7978-9045
Angela DunnAdult and Child Center for Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado, USA.
Isabella ZanilettiChildren's Hospital Association, Lenexa, Kansas, USA.
Kathryn ColbornAdult and Child Center for Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado, USA.
Derek J WilliamsDepartment of Pediatrics, Division of Hospital Medicine Monroe Carell Jr Children's Hospital at VUMC, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0003-0295-1240
Sriram RamgopalDepartment of Pediatrics, Division of Emergency Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-1389-5726
Cristin Q FritzDepartment of Pediatrics, Division of Hospital Medicine Monroe Carell Jr Children's Hospital at VUMC, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0001-5587-730X
Maia TaftDepartment of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-4976-969X
Matthew HallChildren's Hospital Association, Lenexa, Kansas, USA.ORCID https://orcid.org/0000-0001-7778-5887
Elizabeth TemteChildren's Hospital Colorado, Aurora, Colorado, USA.
Eric CoonSeattle Children's Hospital, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-7297-8348
Allison KempeAdult and Child Center for Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado, USA.
Lilliam AmbroggioSections of Hospital Medicine and Emergency Medicine, Children's Hospital Colorado and Department of Pediatrics, University of Colorado, Aurora, Colorado, USA.

Funding

AHRQ HHS 1K08HS029693AHRQ HHS K08 HS029693AHRQ HHS P30 HS029767
6 · The paper itself

Abstract

We evaluated whether peripheral intravenous catheter (PIV) utilization and complications (i.e., infiltration/extravasation) differed between children hospitalized with pneumonia who received initial oral versus intravenous antibiotics. In a retrospective cohort study of children hospitalized with pneumonia at four affiliated sites within a single hospital system from 2014 to 2020, we evaluated PIV outcomes and compared them using bivariable analyses and multivariable regression models. Among 1035 children, 65% received initial oral antibiotics and 59% had PIVs. PIVs were placed in 38% of children with oral antibiotics and 99% with IV antibiotics. Infiltration/extravasation occurred in 1% of children with oral antibiotics and 9% with IV antibiotics. Among children with PIVs, those with oral antibiotics had lower odds of infiltration/extravasation (odds ratio [OR]: 0.39, 95% confidence interval [CI]: 0.17-0.9). Given the pain and anxiety of PIVs for children and the morbidity associated with infiltrations/extravasations, initial oral antibiotics provide an opportunity to improve patient and family experiences and minimize PIV-related harms.

Indexed as

Anti-Bacterial AgentsCatheterization, PeripheralPneumoniaAdministration, IntravenousAdministration, OralChildChild, PreschoolFemaleHospitalizationHumansInfantMaleRetrospective StudiesAnti-Bacterial Agents

Identifiers

PMID41133916
PMCPMC12598763

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.