ReviewCurrent neuropharmacology2026
Neutrophil Extracellular Traps in Central Nervous System Diseases.
Review in Current neuropharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Neutrophil Elastase-Responsive Linkers for Precision Antibody-Drug Conjugates.ACS medicinal chemistry letters · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Neutrophil Extracellular Traps (NETs) are complexes containing DNA fibrils and antimicrobial peptides that are released by neutrophils in response to pathogen stimulation. At the time of their discovery, the neutrophil extracellular trap contained active substances such as Neutrophil Elastase (NE) and myeloperoxidase (MPO). Although NETs were initially thought to be a means for the innate immune system to fight microbial invasion, now they have been observed to have a broader impact throughout the body. In recent studies, NETs have been linked to several neurological disorders and have been found to have varying roles in a number of diseases. In addition to their role in thrombosis, NETs have been identified in various autoimmune diseases. NETs play a significant role in the body when they are produced at the correct time and place; however, when the generation and removal of NETs are out of equilibrium, there can be important implications for human health. Here, the impact of NETs is reviewed in various neurological disorders and their potential clinical applications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.