Evidence map›Paper›PMID 41133761›Full record

ArticleACS synthetic biology2025

The Translational Coupling of Daidzein Reductase and Dihydrodaidzein Racemase Genes Improves the Production of Equol and Its Analogous Derivatives in Engineered Lactic Acid Bacteria.

Susana Langa, José Antonio Curiel, Ángela Peirotén, José María Landete

Abstract read
In one paragraph

Article in ACS synthetic biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Susana LangaDepartamento de Tecnología de Alimentos, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Crta de la Coruña Km7.5, 28040 Madrid, Spain.
José Antonio CurielDepartamento de Tecnología de Alimentos, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Crta de la Coruña Km7.5, 28040 Madrid, Spain.
Ángela PeiroténDepartamento de Tecnología de Alimentos, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Crta de la Coruña Km7.5, 28040 Madrid, Spain.ORCID 0000-0002-1532-8530
José María LandeteDepartamento de Tecnología de Alimentos, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Crta de la Coruña Km7.5, 28040 Madrid, Spain.ORCID 0000-0002-5147-3989

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Equol (EQ) and its analogous derivatives 5-hydroxy-equol (5-OH-EQ) and 5-hydroxy-dehydroequol (5-OH-D-EQ) are isoflavones which benefit human health. They are produced from daidzein and genistein, respectively, in the gut by microorganisms harboring the genes daidzein reductase (

Indexed as

EquolIsoflavonesLactobacillalesMetabolic EngineeringOxidoreductasesRacemases and EpimerasesdaidzeindihydrodaidzeinEquolIsoflavonesOxidoreductasesRacemases and Epimerases5-hydroxy-dehydroequol5-hydroxy-equoldihydrodaidzein racemasehealthsoy beveragestranslational coupling

Identifiers

PMID41133761
PMCPMC12645574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.