Evidence map›Paper›PMID 41133664›Full record

ArticleClocks & sleep2025

Reporter-Mediated Evaluation of the Circadian Oscillations of

Kaitlyn Chhe, Bhavna Kalyanaraman, Sophie A Spielberger, Hui-Hsien Lin, Stephanie R Taylor, Michelle E Farkas

Abstract read
In one paragraph

Article in Clocks & sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kaitlyn ChheDepartment of Chemistry, University of Massachusetts Amherst, Amherst, MA 01003, USA.ORCID 0009-0000-2165-9283
Bhavna KalyanaramanDepartment of Chemistry, University of Massachusetts Amherst, Amherst, MA 01003, USA.ORCID 0000-0003-3652-4730
Sophie A SpielbergerDepartment of Biology, University of Massachusetts Amherst, Amherst, MA 01003, USA.ORCID 0009-0009-2846-859X
Hui-Hsien LinDepartment of Chemistry, University of Massachusetts Amherst, Amherst, MA 01003, USA.ORCID 0000-0002-7394-653X
Stephanie R TaylorDepartment of Computer Science, Colby College, Waterville, ME 04901, USA.ORCID 0000-0003-3562-6479
Michelle E FarkasDepartment of Chemistry, University of Massachusetts Amherst, Amherst, MA 01003, USA.ORCID 0000-0001-5824-1243

Funding

Chemical Biology Approaches for Studying Circadian RhythmsR35GM143016 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI FARKAS, MICHELLE ELIZABETH · 2021 to 2025
$1.9M
NIGMS NIH HHS R35 GM143016NIH HHS 4R35GM143016-04
6 · The paper itself

Abstract

The protein SNAIL has been widely studied for its roles in promoting cancer invasion and resistance to apoptosis. There are multiple contributors to its expression, including self- and circadian regulation, and it has been posited that

Indexed as

breast cancercancer biologycircadian rhythmsepithelial-to-mesenchymal transition (EMT)luciferase reportersMCF10A cellsMCF7 cellsMDA-MB-231 cellsrhythmicitySNAILU2OS cells

Identifiers

PMID41133664
PMCPMC12550899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.