Evidence map›Paper›PMID 41133545›Full record

ArticleReports (MDPI)2025

Arctic Sun Surface Temperature Management Device for Neuroprotection During Pregnancy-A Short Case Report and Review of the Literature.

Vasileios Vazgiourakis, Konstantinos Mantzarlis, Konstantina Deskata, Asimina Valsamaki, Foteini Bardaka, Dimitra Bagka, George Dimopoulos, Demostenes Makris

Abstract readCase Reports
In one paragraph

Article in Reports (MDPI), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vasileios VazgiourakisDepartment of Critical Care, University Hospital of Larissa, Mezourlo, 41110 Larissa, Greece.ORCID 0000-0002-6747-1961
Konstantinos MantzarlisDepartment of Critical Care, University Hospital of Larissa, Mezourlo, 41110 Larissa, Greece.ORCID 0000-0002-2453-5398
Konstantina DeskataDepartment of Critical Care, University Hospital of Larissa, Mezourlo, 41110 Larissa, Greece.
Asimina ValsamakiDepartment of Critical Care, University Hospital of Larissa, Mezourlo, 41110 Larissa, Greece.ORCID 0000-0001-8814-0371
Foteini BardakaDepartment of Critical Care, University Hospital of Larissa, Mezourlo, 41110 Larissa, Greece.
Dimitra BagkaDepartment of Critical Care, University Hospital of Larissa, Mezourlo, 41110 Larissa, Greece.
George DimopoulosThird Department of Critical Care Medicine, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Demostenes MakrisDepartment of Critical Care, University Hospital of Larissa, Mezourlo, 41110 Larissa, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeted temperature management (TTM), particularly the avoidance of hyperpyrexia, is a cornerstone of intensive care, especially in conditions such as cerebral edema and increased intracranial pressure. Management becomes more complex in pregnancy, where maternal neuroprotection must be weighed against fetal safety. Both invasive and noninvasive methods for temperature control have been described, but evidence regarding their safety in pregnancy remains limited. We present the case of a 24-year-old pregnant woman admitted to the ICU with cerebral edema due to subdural empyema. The Arctic Sun surface cooling system was employed for fever control, with continuous maternal and fetal monitoring. The system effectively maintained normothermia without immediate adverse effects on either the mother or the fetus. However, on the third day of its use, the patient experienced a spontaneous preterm delivery of a stillborn fetus. Although a causal link between surface cooling and preterm labor cannot be established from this single case, the event underscores the need for caution and further investigation. This case highlights both the feasibility and the uncertainties of using advanced TTM devices in critically ill pregnant patients. It emphasizes the importance of multidisciplinary monitoring and the urgent need for evidence-based guidelines to balance maternal benefits with fetal safety.

Indexed as

arctic sunhyperpyrexianeuroprotectionpregnancytemperature control systems

Identifiers

PMID41133545
PMCPMC12643448

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.