Evidence map›Paper›PMID 41133326›Full record

ArticleThe British journal of psychiatry : the journal of mental science2025

Trajectories of depression across key events in later life: findings from the English Longitudinal Study of Ageing.

Brian Beach, Eun-Jung Shim, Eleonora Iob, Paola Zaninotto

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Article in The British journal of psychiatry : the journal of mental science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Brian BeachResearch Department of Epidemiology & Public Health, University College London, London, UK.ORCID https://orcid.org/0000-0002-5917-2531
Eun-Jung ShimDepartment of Psychology, https://ror.org/01an57a31Pusan National University, Busan, Republic of Korea.ORCID https://orcid.org/0000-0001-9807-462X
Eleonora IobResearch Department of Behavioural Science & Health, University College London, London, UK.ORCID https://orcid.org/0000-0003-3617-0266
Paola ZaninottoResearch Department of Epidemiology & Public Health, University College London, London, UK.ORCID https://orcid.org/0000-0003-3036-0499

Funding

Project-001R01AG017644 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI Andrew Steptoe · 2000 to 2026
$56.2M
NIA NIH HHS R01 AG017644
6 · The paper itself

Abstract

backgroundVarious key events characterise experiences in later life, such as retirement, bereavement, caregiving, developing long-term conditions and hospital admission. Given their potential to disrupt lives, such events may affect older people's mental health, but research on the associations between such events and depression has produced inconsistent findings.

aimsTo investigate the impact of key events in later life on depression trajectories in a representative cohort of people aged 50-69 in England.

methodOur sample draws on 6890 respondents aged 50-69 in Wave 1 (2002/2003) of the English Longitudinal Study of Ageing, following them through to Wave 9 (2018/2019). We measured depression using the eight-item Center for Epidemiological Studies Depression scale. Later life events included retirement, spouse/partner death, becoming an unpaid caregiver, developing a limiting long-term illness and hospital admissions because of a fall or non-fall causes. Piecewise mixed-effects logistic regression models tested for changes in the trajectories of depression before and after each event.

resultsStatistically significant improvements in the trajectory of depression were observed following spousal bereavement, one's own retirement and hospital admission because of causes other than falls, with reductions in the odds of depression of 48% (odds ratio: 0.52 (95% CI: 0.44-0.61)), 15% (0.85 (0.78-0.92)) and 4% (0.96 (0.94-0.99)), respectively. No changes were associated with developing a limiting long-term illness, becoming an unpaid caregiver or following spousal retirement or a hospital admission because of a fall.

conclusionsThe findings highlight the relative resilience among older adults in England in terms of depression following key later life events. There is still a role to play in delivering mental health support for older people following such events, particularly by improving the identification of those at risk of certain events as part of a broader strategy of prevention. Findings also underscore the importance of partner/spousal circumstances on individual mental health.

Indexed as

Ageingdepressive disordersepidemiologyresiliencestatistical methodology

Identifiers

PMID41133326
PMCPMC12614320

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