Evidence map›Paper›PMID 41133241›Full record

ArticleChemical science2025

Desulfurative modification of cysteine residues in peptides and proteins

Zijing Chen, Wenjun Wang, Baicheng Chen, Si-Cong Chen, Aimila Aoken, Fanrui Wu, Guihua Zeng, Tuoping Luo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zijing ChenKey Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Beijing National Laboratory for Molecular Science, College of Chemistry and Molecular Engineering, Peking University Beijing 100871 China tuopingluo@pku.edu.cn.
Wenjun WangDepartment of Chemistry, The Hong Kong University of Science and Technology Hong Kong 999077 China.
Baicheng ChenKey Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Beijing National Laboratory for Molecular Science, College of Chemistry and Molecular Engineering, Peking University Beijing 100871 China tuopingluo@pku.edu.cn.
Si-Cong ChenInstitute of Molecular Physiology, Shenzhen Bay Laboratory Shenzhen Guangdong 518055 China.
Aimila AokenPeking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University Beijing 100871 China.
Fanrui WuKey Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Beijing National Laboratory for Molecular Science, College of Chemistry and Molecular Engineering, Peking University Beijing 100871 China tuopingluo@pku.edu.cn.
Guihua ZengInstitute of Molecular Physiology, Shenzhen Bay Laboratory Shenzhen Guangdong 518055 China.
Tuoping LuoKey Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Beijing National Laboratory for Molecular Science, College of Chemistry and Molecular Engineering, Peking University Beijing 100871 China tuopingluo@pku.edu.cn.ORCID https://orcid.org/0000-0003-2156-3198

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Late-stage modification of peptides and post-translational modifications of proteins are of significant value in research, drug discovery and therapeutic development. We report the discovery of novel photoactivity in the thieno[2,3-

Identifiers

PMID41133241
PMCPMC12542026

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.