ArticleJournal of tropical medicine2025
A Preliminary Study on Clinical Characteristics of Patients With Autoimmune Liver Following Coronavirus Disease 2019.
Article in Journal of tropical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to investigate the clinical features of patients with autoimmune liver disease (AILD) following coronavirus disease 2019 (COVID-19). Methods: For the AILD group, 19 inpatients who were first diagnosed with AILD were enrolled from Wuxi Fifth People's Hospital between January 2021 and December 2021. The post-COVID-19 AILD group comprised seven patients recruited after December 2022 who were initially diagnosed with COVID-19 and later diagnosed with AILD. Routine blood indices, biochemical parameters, serum-related antibodies, and serum immunoglobulin levels were assessed in the two groups. Ultrasound-guided liver biopsy was performed to observe the pathological characteristics of the liver in the two groups. The expression of immune indices in the two groups was observed by immunohistochemistry. Results: The age and calcium levels of the post-COVID-19 AILD patients were significantly lower than those of the AILD patients ( Conclusion: AILD following COVID-19 has typical AILD characteristics, including acute onset, but has other characteristics that allow it to be distinguished from other AILDs.
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