Evidence map›Paper›PMID 41133207›Full record

ArticleLancet regional health. Americas2025

The cost of inaction to strengthen the resilience of primary health care in Latin America and the Caribbean: a modelling study.

Tharindu Wickramaarachchi, Nick Scott, Pablo Villalobos Dintrans, Marina Gonzalez-Samano, Manuela Villar Uribe

Abstract read
In one paragraph

Article in Lancet regional health. Americas, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tharindu WickramaarachchiDisease Elimination Program, Burnet Institute, Melbourne, Australia.
Nick ScottDisease Elimination Program, Burnet Institute, Melbourne, Australia.
Pablo Villalobos DintransFacultad de Medicina y Ciencias de la Salud, Universidad Mayor, Santiago, Chile.
Marina Gonzalez-SamanoDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Manuela Villar UribeHealth Nutrition and Population, The World Bank, Washington, DC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Latin America and the Caribbean (LAC) region will face future public health emergencies due to pandemics, natural disasters, migration, economic crisis or other unforeseen events. These events disrupt healthcare service coverage with consequences for morbidity, mortality and economic productivity. This study aimed to estimate the health and economic cost of potential future health system shocks, as a proxy for the cost of inaction to strengthen the resilience of primary health care. Methods: For 33 countries in LAC, primary health care shock scenarios were modelled as short-term reductions to the coverage of antenatal care and child health interventions using the Lives Saved Tool, and to family planning services and non-communicable disease management using custom models. Primary health care shocks starting in 2026 and leading to 25-50% relative coverage reductions (50% being a COVID-19-like disruption) with recovery periods of one to five years were compared to a strengthened primary health care scenario with intervention coverage maintained. Excess deaths and unintended pregnancies were estimated for 2026-2030 and converted to lifetime societal economic costs with 3% per annum discounting based on years of life lost (deaths) and reduced workforce productivity (unintended pregnancies). Findings: Depending on the magnitude and recovery time, the modelled primary health care shocks resulted in an additional 600-3100 stillbirths, 300-1400 neonatal deaths, 2000-10,000 child deaths, 2200-11,300 maternal deaths, 29,000-149,000 non-communicable disease deaths, and 2.7-14.1 million unintended pregnancies over 2026-2030. This translates to US$7-37 billion in societal economic costs per primary health care shock. Interpretation: Substantive investment in primary health care resilience would be warranted to limit the potential impact of health system shocks on service coverage. Funding: The World Bank.

Indexed as

Antenatal careCost of inactionFamily planningLatin America and the CaribbeanModellingNon-communicable diseasesPrimary health care

Identifiers

PMID41133207
PMCPMC12541822

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.