Evidence map›Paper›PMID 41133156›Full record

ArticleFrontiers in medicine2025

Dynamic biomechanical equilibrium in pelvic organ prolapse: from mechanistic insights to precision reconstruction.

Daoming Tian, Qian Luo, Xingqi Wang, Yubin Wen, Yuan Li, Jiangna Gu, Hongcheng Li, Jihong Shen, Ling Li

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daoming Tian *Department of Urology, Kunming Medical University First Afiliated Hospital, Kunming, China.
Qian Luo *Department of Urology, Kunming Medical University First Afiliated Hospital, Kunming, China.
Xingqi WangDepartment of Urology, Kunming Medical University First Afiliated Hospital, Kunming, China.
Yubin WenDepartment of Urology, Kunming Medical University First Afiliated Hospital, Kunming, China.
Yuan LiDepartment of Urology, Kunming Medical University First Afiliated Hospital, Kunming, China.
Jiangna GuDepartment of Urology, Kunming Medical University First Afiliated Hospital, Kunming, China.
Hongcheng LiDepartment of Urology, Kunming Medical University First Afiliated Hospital, Kunming, China.
Jihong ShenDepartment of Urology, Kunming Medical University First Afiliated Hospital, Kunming, China.
Ling LiDepartment of Urology, Kunming Medical University First Afiliated Hospital, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The traditional treatment of pelvic floor organ prolapse (POP) is based on static anatomical repair, but the postoperative recurrence rate is still high in the surgical rate, which suggests the need to re-examine its pathogenesis from a biomechanical perspective. Objective: To propose a new concept of POP prevention and treatment centered on the dynamic mechanical balance system of the levator plate-perineum and posterior vaginal vault, and to provide a theoretical basis for clinical intervention. Results: This study reveals the key mechanisms of the pelvic floor dynamic balance system through biomechanical analysis. The stability of the pelvic floor is maintained by three synergistic aspects: first, the triangular support structure composed of the bladder-uterus-tibial plate realizes effective stress transmission; second, the posterior fornix of the vagina serves as a mechanical fulcrum, guiding the uterus to produce the characteristic "downward-backward" displacement; and lastly, the 90° functional folding angle of the vagina ensures the reasonable distribution of the loads. When this sophisticated system becomes unbalanced due to birth injury or aging, it leads to abnormal stress transmission and organ displacement, ultimately leading to prolapse symptoms. Conclusion: Shifting from static repair to dynamic mechanical balance reconstruction is the key to improving POP efficacy, and individualized mechanical repair strategies and long-term maintenance mechanisms need to be further explored in the future.

Indexed as

biomechanicslevator platepelvic organ prolapseposterior fornixreconstructive surgery

Identifiers

PMID41133156
PMCPMC12542915

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.