Evidence map›Paper›PMID 41133085›Full record

ArticleCureus2025

Angiography-Guided Limb Salvage Planning in a Surgical Candidate With Gas Gangrene of the Foot.

Murali K Manikkavelu, Venkatesh Aadhe, Raven Sands, Frederick Tiesenga, Mahamed Jama

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Murali K ManikkaveluGeneral Surgery, Community First Medical Center, Chicago, USA.
Venkatesh AadheMedicine, Windsor University School of Medicine, Basseterre, KNA.
Raven SandsMedicine, Windsor University School of Medicine, Basseterre, KNA.
Frederick TiesengaGeneral Surgery, Community First Medical Center, Chicago, USA.
Mahamed JamaMedicine, All Saints Medical School, Roseau, DMA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gas gangrene is a fulminant soft-tissue infection that requires rapid intervention to prevent extensive tissue destruction and mortality. Diabetic patients with peripheral neuropathy often have delayed recognition of injuries and impaired wound healing, placing them at substantially higher risk of severe complications. This report presents a 60-year-old male patient with diabetes and peripheral neuropathy who developed gas gangrene of the right foot. Despite two initial debridements, concern remained for progressive infection necessitating limb amputation. An abdominal aortogram with run-off demonstrated preserved distal perfusion of the right lower extremity, allowing the surgical team to consider below-the-knee amputation (BKA) rather than above-the-knee amputation (AKA). BKA allows for improved prosthetic fitting and lower energy expenditure during ambulation, which is preferable to the outcomes typically seen with AKA. Ultimately, the patient chose to defer amputation and arranged for outpatient follow-up to revisit the decision at a later time. This case underscores the role of angiography in guiding amputation planning and highlights the need to balance clinical judgment with patient autonomy in limb salvage decisions.

Indexed as

below the knee amputationclostridial myonecrosisct angiogramdebridementdiabetic foot infectiongas gangrenelimb salvagepatient autonomysurgical decision-makingvascular imaging

Identifiers

PMID41133085
PMCPMC12543007

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.