ArticleCureus2025
Patterns of Antibiotic Resistance in Community-Acquired Infections: A Study From a Tertiary Care Hospital.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Analysis of the effectiveness of improving the testing rate of pathogenicity specimens prior to the use of antibiotics in Shandong Province, 2014-2023.Frontiers in public health · 2025Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntibiotic resistance in community-acquired infections (CAIs) has emerged as a growing global concern with serious clinical and public health implications. Rising resistance to first-line therapies is reducing treatment effectiveness, increasing healthcare costs, and contributing to higher morbidity and mortality.
objectiveThe objective is to evaluate the patterns of antibiotic resistance among bacterial isolates from CAIs in patients presenting to a tertiary care hospital and to assess their associated clinical outcomes to inform empirical therapy and support antimicrobial stewardship initiatives. METHODOLOGY: A descriptive observational study was conducted at the Microbiology Department of Gujranwala Medical College, Gujranwala, Pakistan, from February 11, 2024, to February 11, 2025. The study included 560 individuals with suspected CAIs who tested positive for bacterial infection. Antimicrobial susceptibility testing was performed using the Kirby-Bauer disc diffusion method in accordance with Clinical and Laboratory Standards Institute guidelines. Data analysis was conducted using Statistical Package for the Social Sciences version 26 (IBM Corp., Armonk, NY).
resultsOf the 560 patients, 314 (56.07%) were men and 246 (43.93%) were women; 188 patients (33.57%) were aged 18-40 years. The most common specimen was urine (n = 234, 41.79%), followed by blood (n = 112, 20.00%). The predominant pathogens were
conclusionThis study demonstrates a high burden of MDR organisms in CAIs, with poor clinical outcomes, particularly in carbapenem-resistant and MRSA infections. These findings emphasize the urgent need for strengthened antimicrobial stewardship, continuous surveillance of resistance trends, and locally tailored empirical treatment guidelines in community healthcare settings.
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