ArticleCureus2025
Human Epidermal Growth Factor Receptor 2 (HER2/Neu)-Positive Ovarian High-Grade Serous Carcinoma Metastasizing to the Breast: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Metastasis to the breast from malignancies is rare and often poses a diagnostic challenge due to its clinical and radiologic similarity to primary breast cancer. We report the case of a 47-year-old woman who presented with abdominal discomfort, a palpable abdominal mass, and bilateral inguinal lymphadenopathy. Imaging and biopsy revealed high-grade serous carcinoma of Müllerian origin with human epidermal growth factor receptor 2 (HER2/neu) overexpression, which had metastasized to the breast and right axillary lymph nodes. She was treated with a combination chemotherapy regimen of Taxotere, carboplatin, trastuzumab, and pertuzumab (TCHP). This case underscores the importance of distinguishing metastatic involvement of the breast from primary breast cancer to ensure appropriate treatment and management.
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