Evidence map›Paper›PMID 41132960›Full record

ArticleTranslational lung cancer research2025

Actionable mutations and targeted therapy in non-small cell lung cancer among Latin American and Hispanic patients: a systematic literature review of prognosis and meta-analysis.

Juan Pablo Castañeda-González, Jonathan W Riess, María Paula Gómez-Gómez, Daniel Clavijo Cabezas, Merideidy Plazas Vargas, Rafael Parra-Medina

Abstract read
In one paragraph

Article in Translational lung cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juan Pablo Castañeda-GonzálezDepartment of Epidemiology, Fundación Universitaria de Ciencias de la Salud-FUCS, Bogotá, Colombia.ORCID https://orcid.org/0000-0001-5400-9068
Jonathan W RiessDivision of Hematology and Oncology, UC Davis Comprehensive Cancer Center, Sacramento, CA, USA.ORCID https://orcid.org/0000-0001-7370-7304
María Paula Gómez-GómezDepartment of Pathology, Fundación Universitaria de Ciencias de la Salud-FUCS, Bogotá, Colombia.
Daniel Clavijo CabezasDepartment of Pathology, Fundación Universitaria de Ciencias de la Salud-FUCS, Bogotá, Colombia.
Merideidy Plazas VargasDepartment of Epidemiology, Fundación Universitaria de Ciencias de la Salud-FUCS, Bogotá, Colombia.ORCID https://orcid.org/0000-0003-3640-9708
Rafael Parra-MedinaDepartment of Pathology, Fundación Universitaria de Ciencias de la Salud-FUCS, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-8428-5837

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In Latin America, lung cancer is the leading cause of cancer-related death. Oncogenic driver alterations, including Methods: We conducted a systematic literature review of publications and abstracts until June 2024 including observational studies performed with NSCLC Latin population that evaluate the prognostic impact of molecular alterations on survival and progression. Results: We analyzed 47 studies (21,046 patients) reporting the clinical impact of actionable and non-actionable mutations on prognosis. The mean age was 60.5 years, 52.5% were women. Patients treated with first-generation Conclusions: Latino patients with

Indexed as

HispanicLung cancermutationsprognosissystematic review

Identifiers

PMID41132960
PMCPMC12541853

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.