Evidence map›Paper›PMID 41132895›Full record

ArticleEngineering in life sciences2025

Foam Formation in Shake Flasks and Its Consequences.

David Vonester, Kyra Hoffmann, Thomas Palmen, Lena Regestein, Ulrike Richter, Anna-Lena Altenhoff, Maximilian Hoffmann, Yulia Radeva, Jochen Büchs, Jørgen Barsett Magnus

Abstract read
In one paragraph

Article in Engineering in life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Foam Formation in Shake Flasks and Its Consequences.Engineering in life sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

David VonesterAVT - Biochemical Engineering, RWTH Aachen University Aachen Germany.
Kyra HoffmannAVT - Biochemical Engineering, RWTH Aachen University Aachen Germany.
Thomas PalmenAVT - Biochemical Engineering, RWTH Aachen University Aachen Germany.
Lena RegesteinAVT - Biochemical Engineering, RWTH Aachen University Aachen Germany.
Ulrike RichterAVT - Biochemical Engineering, RWTH Aachen University Aachen Germany.
Anna-Lena AltenhoffAVT - Biochemical Engineering, RWTH Aachen University Aachen Germany.
Maximilian HoffmannAVT - Biochemical Engineering, RWTH Aachen University Aachen Germany.
Yulia RadevaAVT - Biochemical Engineering, RWTH Aachen University Aachen Germany.
Jochen BüchsAVT - Biochemical Engineering, RWTH Aachen University Aachen Germany.
Jørgen Barsett MagnusAVT - Biochemical Engineering, RWTH Aachen University Aachen Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foam formation in stirred tank fermentation processes is a well-studied phenomenon. However, foaming in shake flask cultivations is rarely considered. Non-baffled shake flasks, in particular, are generally considered to prevent foaming problems. However, under certain process conditions, foaming in non-baffled shake flasks can occur. In this study, phenomena of foam formation in shake flasks, their impact on the maximum oxygen transfer capacity (OTR

Indexed as

foam formationmaximum oxygen transfer capacityonline viscosity measurementout‐of‐phase phenomenonshake flask

Identifiers

PMID41132895
PMCPMC12541551

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.