Evidence map›Paper›PMID 41132639›Full record

ArticleClinical case reports2025

HNF1β Gene Mutation Leading to a MODY5 With Renal Dysplasia: A Case Report.

Xingfa Han, Xueting Qiu, Rong Jiang, Nian Wang, Zheng Li, Zhimin Ma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xingfa HanEndocrinology Department, Suzhou Hospital, Affiliated Hospital of Medical School Nanjing University Suzhou China.ORCID https://orcid.org/0000-0002-4089-8009
Xueting QiuEndocrinology Department, Suzhou Hospital, Affiliated Hospital of Medical School Nanjing University Suzhou China.
Rong JiangEndocrinology Department, Suzhou Hospital, Affiliated Hospital of Medical School Nanjing University Suzhou China.ORCID https://orcid.org/0000-0001-8558-4217
Nian WangEndocrinology Department, Suzhou Hospital, Affiliated Hospital of Medical School Nanjing University Suzhou China.
Zheng LiEndocrinology Department, Suzhou Hospital, Affiliated Hospital of Medical School Nanjing University Suzhou China.ORCID https://orcid.org/0000-0002-1940-289X
Zhimin MaEndocrinology Department, Suzhou Hospital, Affiliated Hospital of Medical School Nanjing University Suzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes a 20-year-old female MODY5 patient. Genetic testing revealed a heterozygous missense mutation c.452C>G (p.R151G) in HNF1β, identical to the mutation carried by her diabetic mother. This case underscores the importance of genetic testing in young-onset diabetes with renal anomalies, facilitating personalized care and family risk assessment.

Indexed as

electrolyte disordershepatic dysfunctionHNF1β mutationMODY5renal dysplasia

Identifiers

PMID41132639
PMCPMC12540206

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.