Evidence map›Paper›PMID 41132633›Full record

ArticleClinical case reports2025

Structural-Functional Dissociation in TBI Hemiplegia: Meridian-Sinew Therapy Promotes Motor Recovery Despite Corticospinal Tract Damage-A Case Report.

Juyue Hong, Yuchun Zheng, Gengbiao Zhang, Hongyi Zheng, Jinghua Wu, Wenbin Zheng

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juyue HongDepartment of Radiology The Second Affiliated Hospital, Shantou University Medical College Shantou Guangdong China.ORCID https://orcid.org/0009-0003-8022-2948
Yuchun ZhengDepartment of Radiology The Second Affiliated Hospital, Shantou University Medical College Shantou Guangdong China.
Gengbiao ZhangDepartment of Radiology The Second Affiliated Hospital, Shantou University Medical College Shantou Guangdong China.
Hongyi ZhengDepartment of Radiology The Second Affiliated Hospital, Shantou University Medical College Shantou Guangdong China.
Jinghua WuShantou Longhu District Jinrou Traditional Chinese Medicine Research Institute Shantou China.
Wenbin ZhengDepartment of Radiology The Second Affiliated Hospital, Shantou University Medical College Shantou Guangdong China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents neuroimaging analysis of a 31-year-old male patient with hemiplegia secondary to severe traumatic brain injury who was treated with an external therapy of Traditional Chinese Medicine (TCM) called meridian-sinew therapy. The patient exhibited complete right-sided limb paralysis following trauma, with full muscle strength recovery after therapy. Serial diffusion tensor imaging evaluations revealed persistently reduced fractional anisotropy values in the left corticospinal tract (CST.L) below the normal range posttreatment, indicating a structure-function decoupling phenomenon. Despite incomplete restoration of structural integrity in CST.L, significant motor function improvement was observed. The findings suggest that meridian-sinew therapy may promote motor recovery through activation of compensatory networks involving non-CST pathways. This investigation provides neuroimaging evidence supporting the therapeutic efficacy of meridian-sinew therapy in TBI-induced hemiplegia and offers novel insights into potential mechanisms of action.

Indexed as

diffusion tensor imaginghemiplegiamagnetic resonance imagingmeridian‐sinew therapyneuroplasticityrehabilitationtraditional Chinese medicinetraumatic brain injury

Identifiers

PMID41132633
PMCPMC12540192

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.