ArticleFrontiers in nutrition2025
Associations of vitamin D with lipid metabolism, inflammation, and mortality vary by glycemic status and gender: a nationwide prospective study.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Vitamin D Status and Atherogenic Lipid Profiles, Including Lipoprotein(a), in Elite Athletes.Nutrients · 2026Article
- Impact of vitamin D deficiency on hyperlipidemia and hyperuricemia in pregnant women with gestational diabetes mellitus in Bangladesh.BMC endocrine disorders · 2026Article
- New findings in diabetic kidney disease: correlation and enhanced combined diagnostic value of sclerostin and 25(OH)VD.Frontiers in endocrinology · 2026Article
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Authors and funding
8 authors.
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Abstract
Background: We aimed to investigate the associations of 25-hydroxyvitamin D (25OHD) with lipid, inflammatory, and injury biomarkers, and their potential mediating roles in vitamin D-related mortality. Methods: We analyzed data from 4,144 participants in the 2015-2018 National Health and Nutrition Examination Survey (NHANES). Glycemic status was classified using fasting plasma glucose and hemoglobin A1c levels. Key biomarkers were assessed, including visceral adiposity index (VAI) and systemic inflammation response index (SIRI). Multivariate linear regression and restricted cubic spline models examined associations. Results: In females, 25OHD was positively associated with HDL-cholesterol across all glycemic subgroups, and with triglycerides and total cholesterol in the normal glycemic subgroup (all Conclusion: Gender and glycemic status influence the associations between vitamin D and biomarkers, with inflammation potentially mediating the relationship between vitamin D and mortality in prediabetic males.
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