Intravenous Fluids in Hospitalized Patients: A Review of Best Practices.

J Lane Wilson, Matthew Decker, Chelsie Cain

Abstract readReview

In one paragraph

Review in Missouri medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J Lane WilsonAssociate Professor, University of Missouri - Kansas City School of Medicine, Department of Community and Family Medicine, University Health Lakewood Medical Center, Kansas City, Missouri, USA.

Matthew DeckerAssistant Professor, University of Missouri - Kansas City School of Medicine, Department of Community and Family Medicine, University Health Lakewood Medical Center, Kansas City, Missouri, USA.

Chelsie CainAssistant Professor, University of Missouri - Kansas City School of Medicine, Department of Community and Family Medicine, University Health Lakewood Medical Center, Kansas City, Missouri, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Judicious use of intravenous fluids in hospitalized patients can improve outcomes and prevent adverse events. For many clinical scenarios, balanced crystalloids have some advantages over normal saline, though the differences in outcomes are small. Excessive administration of normal saline can cause metabolic acidosis and kidney injury. For conditions with sodium and/or chloride deficits, normal saline is preferred. Hypertonic saline is used to rapidly correct severe acute hyponatremia, and hypotonic fluids are indicated for replacement of free water deficits. Intravenous albumin is indicated in only specific scenarios in the setting of cirrhosis and does not seem to have significant advantages for routine volume resuscitation over crystalloids. When intravenous fluids are administered, patient response should be closely monitored to guide subsequent therapy.

Indexed as

Fluid TherapyAlbuminsCrystalloid SolutionsHospitalizationHumansHyponatremiaInfusions, IntravenousIsotonic SolutionsPractice Guidelines as TopicAlbuminsCrystalloid SolutionsIsotonic Solutions

Identifiers

PMID41132472

PMCPMC12543346

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.