SynthesisBioMed research international2025
Neuropathic Pain Relief Through Transcutaneous Electrical Neuromuscular Stimulation: Insights From a Systematic Review and Meta-Analysis of Clinical Evidence.
Synthesis in BioMed research international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neuropathic Pain Relief Through Transcutaneous Electrical Neuromuscular Stimulation: Insights From a Systematic Review and Meta-Analysis of Clinical Evidence.BioMed research international · 2025Pooled it
- Review
- Re-examining the Disc-Centric Interpretation of Chronic Low Back Pain: A Narrative Review.Cureus · 2026Review
- The pivotal role of immunometabolism in diabetic neuropathy and its potential therapeutic strategies.Frontiers in endocrinology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Transcutaneous electrical neuromuscular stimulation (TENS) is a noninvasive, nonpharmacological, and least expensive technique to improve sensitivity and reduce pain in patients with neuropathy. Evidence reported on the effectiveness of TENS on neuropathy was inconclusive. This study was aimed at providing recent evidence on the effectiveness of TENS for neuropathic pain, using data from randomized controlled trials and nonrandomized studies. Methods: We conducted a comprehensive search across Scopus, CINAHL, Web of Science, Medline, Embase, Cochrane Central Register of Control Trials (CENTRAL), Physiotherapy Evidence Database (Pedro), and Google Scholar from January 1, 1999, to May 5, 2024. Eligible studies included randomized controlled trials and nonrandomized studies on TENS for neuropathic pain, without restrictions based on language or country. Key inclusion criteria were studies on TENS for neuropathic pain, while exclusion criteria included studies on neuropathic pain due to cancer, HIV infection, or stroke. Two independent reviewers selected studies, extracted data, and assessed quality using the GRADE tool. Results: Thirty articles met the eligibility criteria, and 25 were included in the meta-analysis. Overall, TENS slightly reduced neuropathic pain compared to placebo, but this was not clinically significant (SMD = -0.35; 95% CI: -0.90 to 0.10, Conclusions: TENS generally seems to provide a small reduction in neuropathic pain compared with a placebo, other electrotherapies, or other interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.