Evidence map›Paper›PMID 41132384›Full record

ArticlePain reports2025

Autistic women report high levels of pain, pain-related anxiety, and pain interference.

Nathan W Haid, Michelle D Failla, Alexandra Sturm

Abstract read
In one paragraph

Article in Pain reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nathan W HaidCollege of Nursing, The Ohio State University, Columbus, OH, USA.ORCID https://orcid.org/0009-0003-3637-0732
Michelle D FaillaCollege of Nursing, The Ohio State University, Columbus, OH, USA.
Alexandra SturmLoyola Marymount University, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-5060-1838

Funding

Measurement and Mechanisms of Pain in Autistic AdultsR01NS133354 · NINDS · OHIO STATE UNIVERSITY · PI Michelle Dawn Failla · 2023 to 2026
$2.1M
Pain sensitivity and endogenous pain modulation in autistic adultsR21AG080308 · NIA · OHIO STATE UNIVERSITY · PI FAILLA, MICHELLE DAWN · 2023 to 2024
$422k
NIA NIH HHS R21 AG080308NINDS NIH HHS R01 NS133354
6 · The paper itself

Abstract

Introduction: Evidence suggests autistic adults experience pain in different ways compared with nonautistic people. Autistic adults report greater pain-related anxiety, which is associated with increased pain sensitivity, and experience high rates of generalized anxiety. It is not yet clear how generalized anxiety may be related to pain-related anxiety for autistic people. Nonautistic women generally experience more pain sensitivity and pain interference. Thus, autistic women may be at greater risk of experiencing the impact of pain-related anxiety on their daily lives. Objectives: We sought to examine the relationship between pain-related anxiety, generalized anxiety, and pain's interference (eg, daily activities, mood) in autistic women's lives. Methods: The present study included N = 52 autistic adults, assigned female at birth (AFAB), who reported on their pain (Brief Pain Inventory), pain-related anxiety (Pain Anxiety Symptoms Scale-20) and generalized anxiety (Generalized Anxiety Disorder 7-Item scale). Results: In this sample, 65.4% of participants reported pain in the last 24 hours and high rates of pain interference overall. Autistic AFAB people reported high rates of generalized anxiety (11.75 ± 5.19) and pain-related anxiety (48.80 ± 13.54). Only the cognitive pain-related anxiety subscale was significantly correlated with generalized anxiety ( Conclusion: Autistic AFAB people are experiencing high rates of pain, pain interference, anxiety, and pain-related anxiety. Given the relationship between pain and anxiety reported for autistic women, therapies that specifically target pain-related anxiety may have profound impacts on autistic women's quality of life.

Indexed as

AnxietyAutismPainPain anxietyPain interferenceWomen

Identifiers

PMID41132384
PMCPMC12543225

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.