ArticleJournal of clinical medicine research2025
Clinical Significance of the Cardio-Ankle Vascular Index as a Cardiovascular Disease Risk Factor in Japanese Elderly Patients With Obesity.
Article in Journal of clinical medicine research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Clinical Significance of Cardio-Ankle Vascular Index in Stage A/B Heart Failure Patients With Type 2 Diabetes Mellitus.Journal of clinical medicine research · 2026Article
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Abstract
Background: The cardio-ankle vascular index (CAVI) is a physiological marker that indicates systemic arterial stiffness, and several reports have demonstrated its usefulness as a predictor of cardiovascular disease (CVD). However, there have been no studies examining the clinical significance of CAVI limited to elderly patients with obesity. This prospective study aimed to determine the clinical significance of CAVI as a CVD risk factor in Japanese elderly patients with obesity. Methods: This study included a total of 402 Japanese elderly patients with obesity (mean age ± standard deviation: 72 ± 5 years; mean body mass index ± standard deviation: 27.6 ± 2.2 kg/m Results: Group H showed a significantly higher visceral fat area, as measured by abdominal computed tomography, compared to group L. A significant relation with biomarkers, such as homeostasis model assessment of insulin resistance (HOMA-IR); preheparin serum lipoprotein lipase mass (pre-LPL mass) concentration, one of the coronary risk factors; and urinary 8-iso-prostaglandinF2α (U-8-iso-PGF2α) concentration, an indicator of oxidative stress Conclusions: The results of this study indicated that the CAVI increases in the presence of visceral fat accumulation and is significantly associated with key CVD risk factors, such as insulin resistance, low pre-LPL mass, and elevated oxidative stress in Japanese elderly patients with obesity. Furthermore, high CAVI is considered a useful predictor of primary CVD events in such patients.
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