ArticleHealth science reports2025
The Effect of Foot Reflexology on Sleep Quality in Patients With Chronic Lymphocytic Leukemia Under Chemotherapy: A Randomized Controlled Trial.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of manual therapy on physical and mental health promotion in adults: a systematic review and meta-analysis.Frontiers in psychology · 2026Pooled it
- The Effect of Foot Reflexology on Sleep Quality in Patients With Chronic Lymphocytic Leukemia Under Chemotherapy: A Randomized Controlled Trial.Health science reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Chronic lymphocytic leukemia (CLL) frequently causes a range of physical and psychological symptoms, including disrupted sleep. Foot reflexology is thought to promote relaxation and improve sleep quality. This study evaluated its effectiveness in patients with CLL undergoing chemotherapy. Methods: A single-blind randomized controlled trial was conducted with 68 participants ( Results: At baseline, there was no significant difference in PSQI scores between groups (Reflexology: 16.30 ± 1.29 vs. Control: 16.78 ± 1.38; Conclusions: Foot reflexology appears to be a safe and effective complementary intervention to improve sleep quality in patients with CLL. However, the study's limitations, including the lack of a sham control, short-term follow-up, and a relatively small sample size, should be considered. Healthcare providers may cautiously incorporate reflexology into supportive care, ensuring integration with standard treatments and professional guidance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.