Evidence map›Paper›PMID 41132056›Full record

ArticleBritish journal of haematology2025

The impact of JAK2

Ryan Brown, Rebekah Bennett, Clare Crean, Andrew Hindley, Julie McGimpsey, Nicholas Cunningham, Aaron Niblock, Suzanne McPherson, Kathryn Boyd, Allister Foy and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of haematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ryan BrownRegional Molecular Diagnostic Service, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK.ORCID https://orcid.org/0009-0009-8454-7073
Rebekah BennettSchool of Biological Sciences, Queen's University Belfast, Belfast, Northern Ireland, UK.
Clare CreanRegional Molecular Diagnostic Service, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK.
Andrew HindleyRegional Molecular Diagnostic Service, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK.
Julie McGimpseyRegional Molecular Diagnostic Service, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK.
Nicholas CunninghamHaematology Department, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK.
Aaron NiblockHaematology Department, Northern Health and Social Care Trust, Antrim, Northern Ireland, UK.
Suzanne McPhersonHaematology Department, Northern Health and Social Care Trust, Antrim, Northern Ireland, UK.
Kathryn BoydHaematology Department, Southern Health and Social Care Trust, Craigavon, Northern Ireland, UK.
Allister FoyHaematology Department, Southern Health and Social Care Trust, Craigavon, Northern Ireland, UK.
Ciaren GrahamSchool of Biological Sciences, Queen's University Belfast, Belfast, Northern Ireland, UK.
Graeme GreenfieldHaematology Department, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK.
Mary Frances McMullinHaematology Department, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK.
Mark A CatherwoodRegional Molecular Diagnostic Service, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment with pegylated interferon α resulted in a molecular response in 91% of patients with an average decrease in JAK2

Indexed as

Gene FrequencyInterferon-alphaJanus Kinase 2Myeloproliferative DisordersPolyethylene GlycolsAdultAgedFemaleHumansMaleMiddle AgedRecombinant ProteinsInterferon-alphaJAK2 protein, humanJanus Kinase 2peginterferon alfa-2aPolyethylene GlycolsRecombinant ProteinsJAK2myeloproliferative neoplasmpegylated interferon alpha

Identifiers

PMID41132056
PMCPMC12710198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.