Evidence map›Paper›PMID 41131768›Full record

ArticleBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2025

[Clinical characteristics and influencing factors of extraglandular invasion of prostatic ductal adenocarcinoma].

Xiaoyong Yang, Fan Zhang, Lulin Ma, Cheng Liu

Abstract readEnglish Abstract
In one paragraph

Article in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Xiaoyong YangDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.
Fan ZhangDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.
Lulin MaDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.
Cheng LiuDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the differences in perioperative clinical and pathological characteristics of patients with different pathological types of prostate cancer undergoing radical prostatectomy, and to analyze the influencing factors that may affect the extraglandular invasion of ductal adenocarcinoma of the prostate.

methodsRetrospective collection was made of the radical prostatectomy patients who were admitted to Peking University Third Hospital from December 2011 to April 2021. The patients were screened based on inclusion criteria to obtain basic clinical features and postoperative pathological results. According to the pathological results, the patients were divided into ductal adenocarcinoma group (mixed with ductal adenocarcinoma) and acinar adenocarcinoma group, and a 1 ∶1 propensity score matching was performed to compare the differences in clinical characteristics between the two groups. Univariate and multivariate analyses of the factors related to extraglandular invasion were performed in the matched ductal adenocarcinoma groups.

resultsA total of 764 patients with prostate cancer were enrolled in this study, of which 62 patients were confirmed to have ductal adenocarcinoma components by postoperative pathology. There was a statistically significant difference in the proportion of the patients with a history of diabetes in baseline characteristics between the two groups before propensity score matching (29.5%

conclusionProstatic ductal adenocarcinoma has a worse prognosis than simple acinar adenocarcinoma. Perineural invasion is the influencing factor of extraglandular invasion of ductal adenocarcinoma.

Indexed as

AdenocarcinomaCarcinoma, DuctalProstatic NeoplasmsAgedHumansMaleMiddle AgedNeoplasm InvasivenessPropensity ScoreProstatectomyRetrospective StudiesDuctal adenocarcinomaNeoplasm invasivenessProstatectomyProstatic neoplasmsRisk factors

Identifiers

PMID41131768
PMCPMC12549341

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.