ArticlePerfusion2026
Towards goal-directed perfusion - Part II: Temperature dependence of Q
Article in Perfusion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
BackgroundGoal-directed perfusion (GDP) during cardiopulmonary bypass (CPB) seeks to match oxygen delivery with patient-specific metabolic demand, yet determinants of oxygen demand and dynamics of oxygen extraction ratio (OER) are not well characterised in paediatric populations. Building on our GARIX (Global AutoRegressive Integrated model with eXogenous variables and an equilibrium force) model from Part 1, we analysed minute-level intraoperative data to derive clinical insights.MethodsGARIX integrates autoregressive memory, exogenous clinical variables (cardiac index, haemoglobin, arterial oxygen saturation, temperature), and an equilibrium component defining indexed oxygen demand (tVO
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