Evidence map›Paper›PMID 41131587›Full record

ArticleMalaria journal2025

Factors contributing to compliance with Expanded Programme on Immunization and RTS, S/AS01 schedules among children aged 24-40 months in Central Tongu District of Ghana.

Diana Sena Awutey-Hinidza, Margaret Kweku, Thomas Gyan, Martin Adjuik, John Paul Amenu, Jonathan Mawutor Gmanyami, Kwaku P Asante

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Article in Malaria journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Diana Sena Awutey-HinidzaCentral Tongu District Health Directorate, Ghana Health Service, Central Tongu, Ghana. dianasena2018@gmail.com.
Margaret KwekuFred N. Binka School of Public Health, Epidemiology and Biostatistics Department, University of Health and Allied Sciences, Hohoe, Ghana.
Thomas GyanKintampo Health Research Centre (KHRC), Research and Development Division, Ghana Health Service, Kintampo, Ghana.
Martin AdjuikFred N. Binka School of Public Health, Epidemiology and Biostatistics Department, University of Health and Allied Sciences, Hohoe, Ghana.
John Paul AmenuFred N. Binka School of Public Health, Epidemiology and Biostatistics Department, University of Health and Allied Sciences, Hohoe, Ghana.
Jonathan Mawutor GmanyamiGlobal Health and Infectious Diseases Research Group, Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana. jgmanyami@gmail.com.
Kwaku P AsanteKintampo Health Research Centre (KHRC), Research and Development Division, Ghana Health Service, Kintampo, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Expanded Programme on Immunization (EPI) is the most successful global childhood programme in reducing mortality and morbidity from vaccine-preventable diseases. Introducing the RTS, S/AS01 malaria vaccine into the routine health system added additional vaccination visits at 24 months. This study determined the factors contributing to compliance with EPI, including RTS, S/AS01 malaria vaccine schedules in the Central Tongu District of Ghana.

methodsA matched case-control study (1:1) was undertaken between December 2021 and February 2022 among caregivers of children aged 24 to 40 months. Mantel-Haenzel odds ratio and conditional logistic regression analysis were used to determine the strength of association between the level of compliance and independent variables.

resultsOf the 220 caregivers,110 were cases, and 110 were controls. Good knowledge about vaccines and vaccination schedules among caregivers was 62% (n = 139). Caregivers who earned income 46% (OR

conclusionNon-compliance with recommended EPI vaccinations, including RTS,S/AS01, was largely due to socio-economic factors, having information and knowledge about vaccines, immunization schedules, and access to immunization services. Healthcare providers can improve immunization coverage by emphasizing education on vaccines and vaccine schedules, using technologies and making services accessible in Ghana.

Indexed as

CaregiversImmunization ProgramsImmunization ScheduleMalariaMalaria VaccinesAdultCase-Control StudiesChild, PreschoolFemaleGhanaHealth Knowledge, Attitudes, PracticeHumansInfantMaleMiddle AgedVaccines, SyntheticMalaria VaccinesRTS,S-AS01 vaccineVaccines, SyntheticCaregiverChildrenComplianceExpanded Program ImmunizationGhanaImmunizationMalariaRTS,S/AS01SchedulesVaccineVolunteer

Identifiers

PMID41131587
PMCPMC12548178

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.