Trial reportBMC musculoskeletal disorders2025
Exploring feasibility of health-related quality of life assessments and pain diaries in patients undergoing prehabilitation before total knee arthroplasty: a pilot study.
Trial report in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05314985 (Effect of Preoperative Training and Education on Pre- and Postoperative Functional Performance in Patients Awaiting TKA; A Randomized Controlled Trial - a Pilot Study), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Preoperative Training and Education on Pre- and Postoperative Functional Performance in Patients Awaiting TKA; A Randomized Controlled Trial - a Pilot Study
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrehabilitation prior to total knee arthroplasty (TKA) may mitigate deterioration in health-related quality of life (HRQOL) during the preoperative period and support recovery after surgery. However, little is known about the feasibility of systematically monitoring HRQOL and pain through patient-reported outcome measures (PROMs) in this context. This pilot study aimed to evaluate the feasibility of using validated HRQOL questionnaires and daily pain diaries during a prehabilitation programme for patients awaiting (TKA) and up to 12 weeks postoperatively.
methodsTwenty patients (mean age 73 ± 6 years) scheduled for primary unilateral TKA were randomly assigned to an intervention group (IG) or control group (CG). The IG participated in a 4- to 8-week individualised prehabilitation programme involving exercise and education. Feasibility was assessed through the completion rates of daily pain diaries and three HRQOL questionnaires (EQ-5D-5 L, SF-12 and KOOS KRQOL) collected at baseline, preoperatively, and at 6- and 12-weeks postoperatively.
resultsHRQOL questionnaires demonstrated high completion rates across both groups (90%). In contrast, adherence to paper-based pain diaries was suboptimal and notably low (CG: 58%; IG: 47%), falling below the threshold for meaningful analysis. Consequently, pain trajectory over time could not be reliably assessed. No significant group-by-time interaction effects were observed for any HRQOL measure: EQ-5D-5 L (p = 0.67; F = 0.51), KOOS KRQOL (p = 0.72; F = 0.64), SF-12 PCS (p = 0.06; F = 0.50) and MCS (p = 0.36; F = 0.10).
conclusionThis pilot study confirms the feasibility and acceptability of HRQOL questionnaires in older patients undergoing prehabilitation before TKA. However, the low diary completion rates highlight the need for alternative pain-monitoring-approaches - such as electronic formats - to improve data quality in future trials. Preliminary findings suggest potential benefits of prehabilitation, warranting further investigation in larger studies.
trial registrationClinicalTrials.gov Identifier; NCT05314985. Registered 20 July 2021. BASEC-Nr. 2020-03060.
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