Evidence map›Paper›PMID 41131447›Full record

ArticleBMC infectious diseases2025

Molecular characterization of antimicrobial resistance genes and plasmid profiles in enterobacterales isolated from urinary tract infections in rural outpatient women in Otavalo, Ecuador.

Fernanda Hernández-Alomía, Carlos Bastidas-Caldes, Antonella Zambrano, Mario Narváez, Pablo Castillejo

Abstract read
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Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Genomic Diversity and Extended-SpectrumInternational journal of microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fernanda Hernández-Alomía *Grupo de Investigación en Biodiversidad, Medio Ambiente y Salud (BIOMAS), Universidad de las Américas, Quito, 170125, Ecuador.
Carlos Bastidas-Caldes *School of Medicine, Universidad Espíritu Santo, Samborondón, Ecuador.
Antonella ZambranoFacultad de Ingeniería y Ciencias Aplicadas. Ingeniería en Biotecnología, Universidad de Las Américas, Quito, 170125, Ecuador.
Mario NarváezFacultad de Ingeniería y Ciencias Aplicadas. Ingeniería en Biotecnología, Universidad de Las Américas, Quito, 170125, Ecuador.
Pablo CastillejoGrupo de Investigación en Biodiversidad, Medio Ambiente y Salud (BIOMAS), Universidad de las Américas, Quito, 170125, Ecuador. castillejopons@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rise of antibiotic-resistant bacteria poses a significant public health threat, particularly in the context of urinary tract infections (UTIs), which rank as the second most common ambulatory illness. UTIs are often caused by Enterobacterales species, such as Escherichia coli and Klebsiella pneumoniae, with increasing resistance to critical antibiotics complicating treatment. Indigenous rural populations, like those in Ecuador, face unique challenges due to cultural, social, and economic barriers that hinder access to healthcare, exacerbating the issue of antibiotic resistance.

methodsThis study analyzed 154 Enterobacterales strains isolated from ambulatory UTI cases in outpatiens from Otavalo, Ecuador, between October 2021 and February 2022. DNA was extracted, and the presence of antibiotic resistance genes (ARGs) was screened using PCR for extended-spectrum beta-lactamases and carbapenemases. Plasmid incompatibility groups were identified through replicon typing, and multi-locus sequence typing (MLST) was performed to characterize strains.

resultsThe analysis revealed four prevalent ARGs, with bla

conclusionsThis study reveals significant antibiotic resistance among Enterobacterales from urinary tract infections in rural outpatients in Ecuador. The bla

Indexed as

Drug Resistance, BacterialEnterobacteriaceaePlasmidsUrinary Tract InfectionsAdultAgedAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesEcuadorEscherichia coliFemaleHumansKlebsiella pneumoniaeMicrobial Sensitivity TestsMiddle AgedAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesAntimicrobial-resistance genesEscherichia coliKlebsiella pneumoniaePlasmidSequence type

Identifiers

PMID41131447
PMCPMC12548206

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.